42 / 45
Page 78
Notes:
conferenceseries
.com
Volume 8, Issue 2 (Suppl)
Chem Sci J 2017
ISSN: 2150-3494 CSJ, an open access journal
Euro Chemistry 2017
May 11-13, 2017
May 11-13, 2017 Barcelona, Spain
4
th
European Chemistry Congress
Sensors based on biomimetic porphyrin derivatives & their hybrid combinations with photonic
nanoparticles
Eugenia Fagadar-Cosma
Institute of Chemistry Timisoara of Romanian Academy, Romania
M
ost synthetic porphyrins are hydrophobic π-conjugated macrocycles and as a consequence organic building blocks for
supramolecular chemistry, providing in this way the required optoelectronic and morphological properties for a plethora of
novel sensors. Besides, porphyrins possess huge capacity for chemical modifications by peripheral substitution and by using them
in hybrid combination with photonic, electronic and magnetic compounds. Wide band absorption hybrid materials were prepared
from different A
3
B porhyrins and cobalt, manganese and zinc metalloporphyrins and silver or gold nanoparticles with the purpose to
develop optical and electrochemical detection of hydrogen peroxide or other compounds showing potential in earlymedical diagnosis.
The synthesized materials were characterized by UV-vis, fluorescence, FT-IR, AFM, SEM TEM and CV. STEM investigation of the
porphyrin-gold hybrids revealed some dendritic structures produced mainly by porphyrin H- and J-type helicoidal self-aggregation
due to their interaction with gold nanoparticles. Layer-by-layer assembly of gold colloid nanoparticles and cobalt porphyrins on GC
electrodes generated electroactive thin films capable to electrochemically detect minute quantities of H
2
O
2
that are relevant for early
diagnosis in medicine. The Co-porphyrin-gold hybrid was exposed to increased amounts of H
2
O
2
and the changes of the absorption
spectra were monitored by UV-vis spectroscopy, proving the same quality of sensing capacity.
Biography
Eugenia Fagadar-Cosma has completed her PhD in 1997 at Polytechnical University of Timisoara. She is senior scientist, doctoral advisor and coordinator of
Organic Chemistry –Porphyrin Programmes in Institute of Chemistry Timisoara of Romanian Academy. She has published more than 250 peer-reviewed full-
papers, 93 papers in prestigious ISI journals, 8 books and 2 chapters in international volumes, 7 patents and has been serving as an editor to a special issue
(Bentham). She was involved in managing of many FP6 , FP7 and national granted projects. She is reviewer of more than 20 ISI indexed ELSEVIER, SPRINGER
and ACS Journals.
efagadar@yahoo.comEugenia Fagadar-Cosma, Chem Sci J 2017, 8:2(Suppl)
http://dx.doi.org/10.4172/2150-3494-C1-008