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Volume 8
Journal of Biotechnology & Biomaterials
ISSN: 2155-952X Euro Biotechnology 2018
October 11-12, 2018
October 11-12, 2018 | Moscow, Russia
21st European
Biotechnology Congress
conferenceseries.com
Page 19
A new direction for viral infections management
Petrova Natalia Vladimirovna and Emelyanova Alexandra Gennadyevna
Institute of General Pathology and Pathophysiology, Russia
Viral diseases are still one of the most pressing global problems of society throughout the world. The problem of
effectiveness and safety for currently used antiviral therapy is still a major concern; a principally new approaches
and the creation on their basis of the original preparations are strongly required. The development of drugs capable of
boosting host immune response and affecting target molecules involved in viral pathogenesis seems to be very promising
in this respect. Products formulated on the basis of released-active forms of antibodies (RA Abs) meet this needs. The
recent years brought persuasive results of RA Abs efficacy obtained in a variety models against a number of viral diseases.
For instance, in a models of influenza, rota–, rhino– and herpes viruses the reduction of pathogen titers, resolution of
symptoms along with the higher survival rates were demonstrated. For retroviral infection an inhibition of main viral
factors involved in the process of penetration and replication was examined. Apart from that, the drugs demonstrated an
excellent safety profile in full-scale toxicity studies. Thus, drugs on the base of RA Abs seems to be a worthy candidates
for further development and investigation.
Biography
Petrova Natalia Vladimirovna has graduated from Saratov State University named after Chernyshevsky and since that time she launched into the scientific
work. She was honoured to take part in international scientific project Marie Curie Actions: International Research Staff Exchange Scheme (Institutte of
Transfusion Medicine, Berlin). At the moment, she is involved in her Postdoctoral studies at the Institute of General Pathology and Pathophysiology, where
she is currently taking a position of Research Associate. She is a co-author of seven papers in reputed journals.
Petrova Natalia Vladimirovna et al., J Biotechnol Biomater 2018, Volume 8
DOI: 10.4172/2155-952X-C5-100