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conferenceseries
.com
Volume 8, Issue 2 (Suppl)
J Biosens Bioelectron, an open access journal
ISSN: 2155-6210
Euro Biosensors 2017
July 10-11, 2017
July 10-11, 2017 Berlin, Germany
7
th
Euro Biosensors
and Bioelectronics Conference
Three types of nanostructure platforms for plasmonics detection of target molecules on a solid surface or
in a complex medium
Hiroyuki Takei
1
, K Watanabe
1
, J Saito
1
, S Yoneda
1
, M Ebisawa
1
, T Miyashita
1
, K Kato
1
, T Okamoto
2
, H Vieker
3
, A Beyer
3
, N Frese
3
and
A Gölzhäuser
3
1
Toyo University, Japan
2
Advanced Device Laboratory, Japan
3
Bielefeld University, Germany
P
lasmonics is expected to play a growing role in biosensing and environmental monitoring. It is in the area of localized surface
plasmon resonance sensing and surface-enhanced Raman/fluorescence spectroscopies where there is much expectation. It is
crucial to develop techniques for producing requisite nanostructures reproducibly at low costs. Toward this end, we are working on a
number of different techniques. One is based on metal film on nano-spheres (MFON) where randomly-adsorbed SiO
2
nano-spheres
are used as a template. The second method is a chemical method whereby base metal nanoparticles are used as seed for growing silver
nano-structures from AgNO
3
. The third method is based on exploitation of naturally existing nanostructures such as butterfly wing
scales; scales coated with Ag have been shown to be an effective SERS platform. We will discuss pros and cons of these three fabrication
techniques. Furthermore, the method of detection protocols is important. We have been working on different configurations. One
is intended for
in-situ
detection of target molecules on a solid surface, such as residual pesticides on agricultural produces as well as
identification of chemical evidence at a criminal scene. With this in mind, we have prepared a flexible surface coated with noble metal
nanostructures, calling it FlexiSERS. Placing FlexiSERS onto a surface allows
in situ
SERS identification of the chemical species on the
surface. We have also combined a SERS surface with thin layer chromatography, TLC-SERS. This has allowed detecting Raman-active
species in the complex medium such as food.
Biography
Hiroyuki Takei completed his PhD in Applied and Engineering Physics at Cornell University in 1992. Since then, he has been affiliated with various organizations
such as Hitachi Ltd. (Electronics), Lamdagen LLC (Biosensor start-up in silicon valley), Fujirebio Inc. (Medical Diagnostics), and Tokyo Medical and Dental
University. Since 2009, he has been Full Professor in Department of Life Sciences at Toyo University, Japan. His main research interest has been in the field of
“Biosensing and analytical techniques based on plasmonics”.
h_takei@toyo.jpHiroyuki Takei et al., J Biosens Bioelectron 2017, 8:2(Suppl)
DOI: 10.4172/2155-6210-C1-033