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conferenceseries
.com
Volume 7, Issue 5 (Suppl)
Epidemiology (Sunnyvale), an open access journal
ISSN: 2161-1165
Epidemiology 2017
October 23-25, 2017
EPIDEMIOLOGY & PUBLIC HEALTH
October 23-25, 2017 | Paris, France
6
th
International Conference on
Epidemiology (Sunnyvale) 2017, 7:5(Suppl)
DOI: 10.4172/2161-1165-C1-018
LIFESTYLE FACTORS AND GENDER-SPECIFIC RISK OF STROKE IN CHINESE ADULTS
WITH HYPERTENSION: ANATIONAL CASE-CONTROL STUDY
Jian Guo
a
, Tianjia Guan
a
, Yuanli Liu
a
, Ying Shen
b
, Baohua Chao
c
, Mei Li
d
and
Longde Wang
e
a
Peking Union Medical College, P.R.China
b
Xuanwu Hospital Capital Medical University, P.R.China
c
National Health and Family Planning Commission of the People’s Republic of China, P.R.China
d
China Stroke Data Center, P.R.China
e
Peking University Health Science Center, P.R.China
L
imited studies investigated the relationship between lifestyle factors and risk of stroke in hypertensive people. Moreover,
estrogen was shown to counteract the unfavourable effects of lifestyle factors on stroke in general people by several studies.
Therefore, we conducted a case-control study to investigate the relationship between lifestyle factors and gender-specific risk of
stroke in hypertensive people based on the China National Stroke Screening Survey. Stroke cases and types were defined by self-
report and were confirmed by a neurologist using neuroimaging according to the criteria of the World Health Organization.
Demographic data and information on risk factors were collected using structured questionnaires and physical examinations.
Hypertensive participants who were diagnosed with ischemic stroke or haemorrhagic stroke were considered cases. The
controls (1:1 frequency-matched for age and urban/rural ratio) were non-stroke subjects who were randomly selected from
the hypertensive participants. A total of 7,631 ischemic stroke cases (7,769 controls) and 994 haemorrhagic stroke cases (1,015
controls) were included. Among smoking, overweight and physical inactivity, the lifestyle factor that showed the strongest
association with the risk of ischemic stroke was physical inactivity (OR=1.42) in men and smoking (OR=1.46) in women. The
strength of the association between physical inactivity and risk of haemorrhagic stroke was higher in men (OR=1.91) than
in women (OR=1.55). In conclusion, the strength of the association between physical inactivity and both types of stroke was
higher in men, but the association between smoking and risk of ischemic stroke was higher in women.