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Journal of Ecosystem & Ecography | ISSN: 2157-7625 | Volume 8
July 11-12, 2018 | Toronto, Canada
International Conference on
Environmental Microbiology & Microbial Ecology
International Conference on
Ecology, Ecosystems & Conservation Biology
&
Acute febrile illness in India– Dengue or Typhoid or both?
Ashima Chugh, Ankur Gupta, Sandhya Bansal
and
Sanjeev Bansal
Bansal Hospital, India
Introduction:
Developing nations share the highest burden of dengue or typhoid due to expeditious population growth, and
restrained safe water and health systems. Laboratory diagnosis of enteric fever includes Blood culture, Stool Culture, and
Serological test. Blood culture is accounted as the gold standard. Easy availability and ubiquitous use of antibiotics make it
frequently difficult to isolate the organism from blood culture. Widal test is the commonest test in developing countries.
Materials and Methods:
50 serum specimens of the patients presented with acute febrile illness & dengue NS1 positive were
taken in the year 2017 at Bansal Hospital, New Delhi. All these patients conferred with acute febrile illness and with the
symptoms common to both typhoid and dengue. The tests applied to the actual diagnosis were a Widal test, typhi dot, NS1 Ag
and dengue serology (IgG and IgM).
Results:
Of the 50 febrile sera samples tested here all were NS1 positive. Case Fatality Rate (CFR) was zero. Around 50% of
patients were less than 18 years. 32 NS1 positive patients had platelet counts less than 50000 (64%) but none of them showed
dribble in platelets below 20000. Widal positive cases were 7 out of 50 (14%) dengue positive patients. 5 out of 7 patients were
typhidot IgM positive (71.4 %). 6 widal positive cases were less than 14 years of age. Samples from these 7 widal positive cases
were repeated for next day to see the increasing titer. 2 out of 7 patients which were typhidot positive showed increasing titers
(28.57%).
Conclusion:
While diagnosing a dual infection of typhoid and dengue, we should rely on 2 or 3 screening tests for typhoid.
Increasing titers should be retained in mind. Both dengue and typhoid may lead to many complications if not diagnosed and
handled promptly and can be lethal.
Biography
Ashima chugh is a gold medalist & consultant pathologist in one of the multispecialty hospitals in Delhi. She has completed her senior residency from GB Pant
Hospital, New Delhi. She has keen interest in clinical pathology & microbiology. Her research papers have been published in national & international journals.
chughashima@yahoo.comAshima Chughet al., J Ecosys Ecograph 2018, Volume 8
DOI: 10.4172/2157-7625-C3-038