digestive-diseases-2016_posters-accepted-abstracts

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Volume 6, Issue 8(Suppl) J Gastrointest Dig Syst 2016
ISSN:2161-069X JGDS, an open access journal
Page 59
Notes:
Digestive Diseases 2016
December 08-09, 2016
conferenceseries.com
Digestive Diseases
December 08-09, 2016 Dubai, UAE
International Conference on
Necrotizing Soft Tissue Infections: Clinical Profile, effect of associated co-morbidities, traumatic injuries
and duration of symptoms before admission on hospital stay
Hemant Atri
Fortis Escorts Hospital, India
Introduction: Necrotizing soft tissue infections is used to encompass infections not only of fascia, as in necrotizing fasciitis, but also
of other soft tissue affected. Necrotizing fasciitis is a progressive, fulminant bacterial infection of subcutaneous tissue that spreads
rapidly through the facial planes causing extensive tissue destruction. NSTIs are rare but potentially fatal condition. In the United
States, there is an estimated annual incidence of 0.04 cases per 1000 annually. Early reports of mortality were variable with rates
ranging from 46 to 76% but outcomes have been improving over time. The mainstay of treatment is early and complete surgical
debridement, combined with antimicrobial therapy, close monitoring, and physiologic support. Total debridement of all necrotic
material must be performed until the skin and subcutaneous tissue can no longer be separated from deep fascia. Novel therapeutic
strategies, including hyperbaric oxygen and intravenous immunoglobulin, have been described, but their effect is controversial.
Identification of patients at high risk of mortality is essential for selection of patients that may benefit from future novel treatments
and for development and comparison of future trials.
Study: Retrospective
Aim: To analyze clinical profile, effect of associated co-morbidities, trauma and duration of symptoms before admission on hospital
stay
Study group: 25cases of NSTIs who reported to our hospital during January to December 2015(formula used-ME=z*Sqrt((p(1-p))/N)
Exclusions: deaths (two)
Co-morbidities included: Diabetes mellitus, Chronic liver disease, Respiratory disease, Respiratory disease, Vascular disease,
Dyselectrolytemia
(No patient was found to have any renal disease)
Results: study showed that the disease is more common in males (80%) and in patients with age group 51-60 years (48%), more in
patients with diabetes mellitus (60%),traumatic injuries(32%) and in patients with other co-morbidities(40%). 40% patients had a
history of 10-15 days of illness before presenting to hospital.44% patients had less than 4 days of hospital stay. There is no correlation
between duration of symptoms before admission or hospital stay in patients with associated co-morbidities and trauma. There is
no correlation between duration of symptoms before admission and hospital stay. There is increased hospital stay in patients with
associated co-morbidities especially in liver pathology or electrolyte imbalance compared to other comorbidities
Biography
Hemant Atri has completed his MBBS from P.D.U. Medical College, Rajkot, Gujarat and currently pursuing Post-graduation in DNB Surgery at Fortis Escorts Hospital,
Faridabad, India.
Hemant Atri, J Gastrointest Dig Syst 2016, 6:8(Suppl)