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conferenceseries
.com
Volume 7, Issue 6 (Suppl)
J Alzheimers Dis Parkinsonism, an open access journal
ISSN: 2161-0460
Dementia 2017
October 16-18, 2017
ALZHEIMER’S DISEASE & DEMENTIA
October 16-18, 2017 | Rome, Italy
9
th
International Conference on
Masked hypertension is associated with cognitive decline in geriatric age
Mustafa Cankurtaran, Mert Esme, Burcu Balam Yavuz, Bunyamin Yavuz, Serkan Asil, Rana Tuna Dogrul, Fatih Sumer, Mustafa Kemal Kilic, Muhammed
Cemal Kizilarslanoglu, Hacer Dogan Varan, Aykut Sagir, Cafer Balci
and
Meltem Halil
1
Hacettepe University, Turkey
2
Ankara Medical Park Hospital, Turkey
3
Gazi University, Turkey
Background:
Masked hypertension is described as high ambulatory blood pressure measurements (ABPM) where office blood
pressure measurements are normal. Effect of hypertension on cognitive functions is well known. However, the effect of masked
hypertension on cognitive functions is still unknown. The aim of this study is to examine the relationship between masked
hypertension and cognitive functions.
Methods:
One hundred-two normotensive patients admitted to the Geriatric Medicine outpatient clinic were included.
Exclusion criteria were hypertension, dementia, major depression, and usage of antihypertensive medication. All patients
underwent ABPM procedures and average daytime blood pressure, mean blood pressure at night and the 24-hours average
blood pressure measurements were recorded. Comprehensive geriatric assessment tests and neuropsychological tests were
administered. The diagnosis of masked hypertension was based on the definitions in the 2013 guideline of the European
Society of Cardiology (ESC).
Results:
44 patients (43%) were diagnosed with masked hypertension. Patients with masked hypertension had significantly
lower scores on Mini-Mental State Examination (MMSE) test, Quick Mild Cognitive Impairment Test (QMCI) and Categorical
Fluency Test than the normotensive patients (p = 0.011; p = 0.046; and p = 0.004; respectively). Montreal Cognitive Assessment
Scale (MOCA) test score was lower in masked hypertension, although this was not statistically significant.
Conclusions:
This study shows that geriatric patients with masked hypertension, compared to normotensive patients have
decreased cognitive functions. ABPM should be performed to normotensive geriatric patients for detecting possible masked
hypertension and in patients with masked hypertension, cognitive assessment is essential to diagnose possible cognitive
dysfunction at early stage.
Biography
Mustafa Cankurtaran is the head of the Geriatric Medicine Department in Hacettepe University. He received his medical degree at 1997 from Hacettepe University.
He completed his Internal Medicine Residency in 2001 and Geriatric Medicine residency in 2004 at the same university. He is currently working as a lecturer and
academician in Hacettepe University Department of Internal Medicine Division of Geriatric Medicine. He has published more than 50 papers in reputed journals.
His special interest is in Alzheimer’s disease, malnutrition, pain management, and other geriatric syndromes.
mustafacankurtaran@gmail.comMustafa Cankurtaran et al., J Alzheimers Dis Parkinsonism 2017, 7:6(Suppl)
DOI: 10.4172/2161-0460-C1-033