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Volume 10
Journal of Earth Science & Climatic Change
Page 28
Climate Congress 2019
May 10-11, 2019
conferenceseries
.com
May 10-11, 2019 Bangkok, Thailand
8
th
World Climate Congress
Endawoke Amsalu et al., J Earth Sci Clim Change 2019, Volume 10
DOI: 10.4172/2157-7617-C2-059
Short-term effect of ambient sulfur dioxide on cause-specific cardiovascular hospital
admission in Beijing, China: A time series study
Endawoke Amsalu and Xiuhua Guo
Capital Medical University, China
E
vidence of the short-term effect of SO
2
on hospital admissions for cause-specific Cardiovascular Diseases
(CVD) is still limited. This study aimed to examine the short-term associations between SO
2
and cause-
specific CVD hospital admission in Beijing. A total of 460,938 hospitalizations for total CVD were obtained
from electronic hospitalization summary reports from 2013 to 2017. A time series analysis was conducted
to investigate the association between SO
2
exposure and hospitalizations for total and cause-specific CVD,
including Coronary Heart Disease (CHD), Atrial Fibrillation (AF) and Heart Failure (HF). Stratified analysis
was also conducted by age group (18-64 years and ≥65 years), sex and season. A generalized additive Quasi-
Poisson model was used to examine the associations between SO
2
and cause-specific CVD after controlling for
seasonality, day of the week, public holidays and weather conditions. We found an almost linear relationship
between the exposure to SO
2
and cause-specific CVD admissions. A 10 µg/m
3
increase in the two-day average
concentration (lag0-1) of SO
2
was associated with an increase of 1.38% (95% CI: 0.99%; 1.77%) in hospital
admission for total CVD, 1.58% (95% CI: 1.16%; 2%) for CHD and 1.69% (95% CI: 0.41%; 2.99%) for AF.
Nevertheless, a statistically significant association was not observed for admissions for HF. The observed
associations in the single-pollutant models were robust to the inclusion of pollutants in the two-pollutant
model, but the estimate was attenuated when adjusting for fine particulate matter (PM
2.5
). No difference in the
association was observed for the effect modifiers of sex, season and age. A statistically significant association
between hospitalizations and SO
2
was observed. The observed association between SO
2
and hospitalization
might not be independent of fine particulate matter (PM
2.5
) and further studies should be conducted to
demonstrate the independent effect of SO
2
.
Biography
Endawoke Amsalu has his expertise in environmental epidemiology focused on air pollution. He is currently pursuing his PhD in the Department
of Epidemiology and Health Statistics. He focuses on non-communicable disease and also infectious disease.
indexmar@outlook.com