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Volume 9
Journal of Obesity & Weight Loss Therapy
ISSN: 2165-7904
JOINT EVENT
Childhood Obesity 2019
Diabetes Conference 2019
March 18-19, 2019
&
3
rd
World Congress on
Diabetes and Obesity
12
th
International Conferences on
Childhood Obesity and Nutrition
March 18-19, 2019 | Rome, Italy
Effect of lactic acid bacteria intake on the health of dam and infant mice
Akie Sato, Shinobu Fujihara
and
Noriko Komatsuzaki
Seitoku University, Japan
W
e examined the effects of the ingestion during pregnancy and lactation of a high-fat diet, a low-calcium diet,
and
Lactobacillus paracasei
NFRI 7415 (LAB) on the health of murine dams and infants. Two experiments were
performed. In experiment 1, we divided 15 pregnant 9-wk-old mice into three equal groups receiving the control
diet, a high-fat diet (HD), or an HD+LAB (HDL) diet during the pregnancy and lactation period. Within 24 hr of
birth, the litters were culled to 10 pups each and nursed by their dams until weaning. After weaning, the liver T-cho
concentration in the HDL group of pups was significantly lower than that of the HD group (
p
<0.05), suggesting that
intake of
Lb. paracasei
has a positive effect on infant helth. In experiment 2, we divided 20 pregnant 9-wk-old mice
into four equal groups receiving the control diet (C), a low-calcium diet (- Ca), a C+LAB (CL) diet, or a -Ca+LAB
(-CaL) diet during the pregnancy and lactation period. Within 24 hr of birth, the litters were culled to 10 pups each
and nursed by their dams until weaning. After weaning, the dams’ body weights and the dietary intake in the C and
the CL groups were significantly higher than those of the -Ca and -CaL groups (
p
<0.05). The bone mass of the CL
group dams was increased compared to those in the other groups. We speculate that the absorption of calcium by
Lb.
paracasei
NFRI 7415 may be enhanced by a sufficient intake of calcium during pregnancy and lactation.
Biography
Akie Sato has completed her PhD in Nutrition from Seitoku University. She currently works as a TeachingAssistant at the Department of Human Nutrition, Seitoku
University.
norikoma@seitoku.ac.jpAkie Sato et al., J Obes Weight Loss Ther 2019, Volume 9
DOI: 10.4172/2165-7904-C1-091