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CNS 2016
December 05-07, 2016
Volume 7, Issue 5(Suppl) J Neurol Neurophysiol
ISSN: 2155-9562 JNN, an open access journal
conferenceseries .com
December 05-07, 2016 Dubai, UAE
2nd International Conference on
Central Nervous System Disorders & Therapeutics
Abdolreza Esnaashari, J Neurol Neurophysiol 2016, 7:5(Suppl)
Clinical correlates of RBD in early Parkinson disease
Abdolreza Esnaashari
Akershus University Hospital, Norway
Objective: Knowledge of the cognitive performance associated with REM sleep behavior disorder (RBD) in newly diagnosed
Parkinson disease (PD) patients is limited. We thus wanted to explore 1) the frequency of RBD in patients with PD at a
relatively early stage and 2) cognitive performance associated with RBD in PD. We hypothesized that RBD would be associated
with cognitive impairment in PD.
Methods: 29 non-demented patients recently diagnosed with PD (disease duration<5 years, Hoehn and Yahr stage <2.5
and no dementia) were recruited. The diagnosis of PD was supported by dopamine transporter SPECT. RBD was diagnosed
based on standardized clinical interview and confirmed by polysomnography. Overall cognition was assessed by screening
tests including the Mini-Mental State Examination (MMSE), and neuropsychological tests of memory, language, executive,
attentional and visuospatial functions tests were performed.
Results: 13 patients (45%) had probable RBD. There were no significant differences between PD with and without RBD in any
of the neuropsychological tests, but a numerically lower performance was observed in the PD RBD group on memory tests
Conclusions: RBD is common even in early PD without dementia, but was not found to be associated significantly with
cognition.
Biography
Abdolreza Esnaashari became a Specialist in Nuclear Medicine in Norway at Akershus University Hospital, Ullevaal University Hospital and Rikshospitalet. He has
co-authored several research papers in neurology.