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conferenceseries
.com
Volume 2, Issue 3 (Suppl)
Breast Can Curr Res, an open access journal
ISSN: 2572-4118
Breast Cancer 2017
June 15-17, 2017
June 15-17, 2017 London, UK
5
th
World Congress on
Breast Cancer
Relationships among body mass index, systemic immune-inflammation index and luminal subtype
in the resistance to endocrine therapy of breast cancer
Qing-xia Li, Dong-jian Shi, Li Li, Jing Zhao, Li-xia Zhang, Na Li, Xin-na Deng
and
Jian-hui Cai
Hebei General Hospital, China
B
reast cancer is the most common cancer for women worldwide. Endocrine therapy has become one of the most important
treatment options for hormone-sensitive patients, which accounts for approximately 70-80% of breast tumors. Many
studies have explored the effect of high BMI on breast cancer patients with endocrine therapy, but the treatment efficacy is
not clear in China. The relationships among BMI, SII and luminal subtype in endocrine therapy of breast cancer have been
rarely explored .We analyzed the data from 161 breast cancer patients ,and demonstrated that the 5-year resistance rates of the
patients in high BMI group and high SII group are significantly higher than that in the normal BMI group and low SII group,
indicating that BMI and SII are closely related to endocrine therapy resistance of luminal type breast cancer. Further analysis
shows that BMI and SII reveal the significantly positive correlation, suggesting that the increase of BMI may promote the
increase of SII in a certain way, and both are involved in the resistance to endocrine therapy.BMI and SII can be the indicators
for the prognosis of luminal type breast cancer, which can not only improve prognostic accuracy, but also reduce the physical
pain and cost toxicity for patients.
Biography
Qing-Xia Li has completed her PhD from The Fourth Military Medical University. She is the Associate Director of the 4th Department of Oncology, Hebei General
Hospital. She has published more than 40 papers in reputed journals and has been serving as an Editorial Board Member of repute.
lqx73@163.comQing-xia Li et al., Breast Can Curr Res 2017, 2:3(Suppl)
DOI: 10.4172/2572-4118-C1-005