breast-cancer-2016_posters-accepted-abstracts

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Volume 8, Issue 8(Suppl) J Cancer Sci Ther
ISSN: 1948-5956 JCST, an open access journal
Page 89
Notes:
Breast Cancer Congress 2016
September 19-21, 2016
conferenceseries.com
Breast Cancer September 19-21, 2016 Phoenix, USA
2nd World Congress on
Importance of a multidisciplinary approach to breast cancer treatment in pregnancy: Case
report of new diagnosis of pregnancy-associated breast cancer
Jeremy Grant and Jessica Hoyson
Western Pennsylvania Hospital, USA
Pregnancy-Associated Breast Cancer (PBAC) is a rare diagnosis and includes new diagnoses of cancer both during
pregnancy as well as within the first year post-delivery. Due to its rarity, there is of yet no gold standard treatment nor is
there sufficient scientific data to support a standardized regimen. We report a case involving a 35-year-old G2P1001 who was
diagnosed with clinical stage II (T2 N1) breast cancer in the second trimester of pregnancy after physical examination revealed
a palpable mass. Ultrasound-guided biopsy revealed poorly differentiated infiltrating ductal carcinoma, nuclear grade 3, with
micropapillary features, ER (90%), PR (25%), positive HER2 positive 3+ with Ki67 index 75%. After extensive counseling and
discussion between Obstetrics, Maternal Fetal Medicine, Breast Surgery, Neonatal ICU, and Oncology, a decision was made to
initiate neoadjuvant therapy with Adriamycin and cyclophosphamide. She completed 4 total NAC treatments prior to delivery
then began weekly Taxol plus Herceptin and Perjeta following delivery. This patient strongly desired to carry the pregnancy to
term and began treatment prior to delivery, making this case unique in comparison to other publications in which treatment
was delayed until after delivery, or the pregnancy was terminated prior to beginning treatment. Our case highlights the
importance of a multi-disciplinary approach to counseling these patients as there remains no gold standard of care at this time.
Biography
Jeremy Grant completed his MD at Temple University School of Medicine in Philadelphia, Pennsylvania. He is a third-year resident in Obstetrics & Gynecology at
Western Pennsylvania Hospital.
Jessica Hoyson completed her MD at Rush University in Chicago, Illinois, and her residency at MetroHealth/Cleveland Clinic in Ohio. She has published
several articles in reputable journals on gynecologic malignancies, minimally invasive surgery, and ethics, a textbook chapter on single-site laparoscopy, and
presented a surgical film at the national meeting for the Society of Gynecologic Oncology. She is currently on staff at the Western Pennsylvania Hospital in the
department of Obstetrics & Gynecology.
Jeremy Grant et al., J Cancer Sci Ther 2016, 8:8(Suppl)