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conferenceseries
.com
Volume 8, Issue 3(Suppl)
J Allergy Ther, an open access journal
ISSN: 2155-6121
Allergy-Clinical Immunology 2017
September 07-08, 2017
September 07-08, 2017 | Edinburgh, Scotland
ALLERGY, ASTHMA & CLINICAL IMMUNOLOGY
11
th
International Conference on
Normocomplementemic urticarial vasculitis in a pediatric patient with chronic sinusitis:Acase report
Anne Melva V Meliton
and
Marysia T Recto
Makati Medical Center, Philippines
A
n eight-year-old female presented with generalized multiple, non-pruritic, erythematous, well-defined irregular-
bordered lesions and wheals which blanched upon pressure on trunk and extremities. The patient had seven months
history of recurrent sinusitis being treated with antibiotics. The lesions were noted one day after discontinuation of seven
days of coamoxiclav. The lesions transformed into erythematous to a slightly violaceous, slightly pruritic non-blanching
type, associated with pain, warmth and edema on joints of the hands, palms and soles. Skin biopsy initially showed findings
consistent with urticaria but clinically, the patient was managed as a case of small vessel vasculitis. The patient was maintained
on oral steroids. Complement levels were normal and lupus panel was negative. There was a diagnostic dilemma between
chronic urticaria and small vessel vasculitis. Re-evaluation of the skin biopsy specimen was done which confirmed urticarial
vasculitis; hence, colchicine was added to the treatment regimen. There was still persistence of the lesions hence she was
referred to a specialty center for allergic conditions in the USA for further evaluation and management. The case was finally
diagnosed as normocomplementemic urticarial vasculitis probably due to chronic infection versus drug-induced (coamoxiclav
versus clindamycin). Hydroxychloroquine was added to control the symptoms and oral steroids were weaned until finally
discontinued. The lesions resolved and the disease was treated accordingly with favorable outcome.
amvmeliton@gmail.comJ Allergy Ther 2017, 8:3(Suppl)
DOI: 10.4172/2155-6121-C1-006