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Volume 4, Issue 4(Suppl)

J Infect Dis Ther 2016

ISSN: 2332-0877, JIDT an open access journal

Page 96

Notes:

Infectious Diseases 2016

August 24-26, 2016

conferenceseries

.com

August 24-26, 2016 Philadelphia, USA

&

Infectious Diseases

Joint Event on

2

nd

World Congress on

Pediatric Care & Pediatric Infectious Diseases

International Conference on

An unusual cause of abdominal pain in a post-menopausal woman with advanced cancer

Gabriela Sanchez Petitto

1

, Rosbel M Brito

2

and

Gabriel M Aisenberg

1

1

University of Texas Health Science Center at Houston, USA

2

Houston Methodist Hospital, USA

A

67-year-old post-menopausal woman with advanced stage histiocytic sarcoma of the pelvis, presented with 4-day history of

abdominal pain and fever. She had local tumor invasion to bladder and cervix requiring bilateral percutaneous nephrostomy

tubes. She received chemotherapy and radiotherapy with partial tumor regression. On examination she had an enlarged suprapubic

mass and foul-smelling vaginal discharge. A computed tomography (CT) scan demonstrated a large cervical mass occluding the

cervical os, causing dilatation of the endometrial cavity, doubling its size compared to one month prior. The patient was started in

broad spectrum antibiotics and a cervical catheterization was intended unsuccessfully. A CT guided percutaneous uterine drain was

placed in her abdomen and purulent drainage grew

Prevotella loescheii

. Blood and urine cultures were negative. She was discharged

under oral sulfamethoxazole/trimethoprim and metronidazole with clinical improvement. In the subsequent months she underwent

chemotherapy and radiotherapy and required long-term percutaneous drainage. Pyometra is defined as the accumulation of pus in the

uterine cavity and thought to be a result of interference with the natural drainage of the uterus. Symptoms are non-specific and easily

misdiagnosed. Diagnosis can be made clinically by drainage of pus from the uterine cavity and with imaging. Treatment includes

drainage along with antibiotics to cover microorganisms such as

Lactobacillus iners

,

Prevotella

spp., and

Lactobacillus crispatus

. Vague

abdominal symptoms in a post-menopausal woman with pelvic malignancy should raise concern for pyometra and prompt treatment

has to be instituted to prevent the development of the most catastrophic complication; uterine perforation.

Biography

Gabriela Sanchez Petitto has completed her MD from the Universidad Central de Venezuela, School of Medicine. She is currently a Postgraduate student of Internal

Medicine at the University of Texas Health Science Center at Houston. She has worked in several projects with hematological malignancies and in the upcoming future with

antibiotic resistance projects.

Gabriela.SanchezPetitto@uth.tmc.edu

Gabriela Sanchez Petitto et al., J Infect Dis Ther 2016, 4:4(Suppl)

http://dx.doi.org/10.4172/2332-0877.C1.009