infectious-diseases-2016_posters-accepted-abstracts

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Volume 4, Issue 4(Suppl) J Infect Dis Ther 2016
ISSN: 2332-0877, JIDT an open access journal
Page 102
Notes:
Infectious Diseases 2016
August 24-26, 2016
conferenceseries.com
August 24-26, 2016 Philadelphia, USA
&
Infectious DiseasesJoint Event on 2nd World Congress on
Pediatric Care & Pediatric Infectious Diseases
International Conference on
Increase of gram negative multi resistance in cases of HAI in a PICU of reference
Andre Ricardo Araujo Da Silva
Federal Fluminense University, Brazil
Multidrug-resistance is a global concern. This is a major problem within intensive care units (ICU), where usually doctors
have few options to treat healthcare associated infections (HAI). The aim of our work is to describe profile of Gram-negative
resistance in cases of HAI occurred in a Pediatric Intensive Care Unit (PICU) of reference. We did a prospective study of all HAI
reported in PICU of Prontobaby-Children’s Hospital, with focus in infections due to Gram-negative bacteria. We used National
Healthcare Safety Network (NHSN) criteria to define HAI. Gram-negative resistance was defined according Magiorakis criteria. In
seven-years of follow-up (from January 2009 to December 2015), we reported 224 HAI. 65 cases were due to Gram-negative and
global rates of resistance reported were 47.7%. HAI rates ranges from 9.4 to 15.1 per 1000 patient-days in PICU, during the study.
In five of seven years, Gram-negative resistance was higher than 50%. During this period only two HAI due to Enterobacteriaceae
resistant to carbapenem were reported (0.9% of all HAI). The main agents founded are Enterobacteriaceae ESBL producers and P.
aeruginosa resistant to carbapenem. In our casuistic, we found higher rates of Gram-negative bacterial resistance in cases of HAI. To
avoid this problem, it is necessary to develop strategies to reduce incidence of HAI, even in critical ill children. Also, new treatment
options are urgently needed.
Biography
Andre Ricardo Araujo Da Silva has completed his PhD from FIOCRUZ-National Institute of Infectology, Brazil. He is an Associate Professor of Neonatology at Federal
Fluminense University, Brazil, Coordinator of Scientific Program of Medicine Course and also leads the Laboratory of Teaching of Prevention and Control of Healthcare
associated infections. He has published more than 15 papers in reputed journals and is a Member of International Federation of Infection Control.
Andre Ricardo Araujo Da Silva, J Infect Dis Ther 2016, 4:4(Suppl)