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conferenceseries.com
March 13-14, 2017 London, UK
3rd Annual Congress and Medicare Expo on
Trauma & Critical Care
Volume 6, Issue 1 (Suppl) J Trauma Treat 2017
ISSN: 2167-1222, JTM an open access journal Trauma 2017
March 13-14, 2017
J Trauma Treat 2017, 6:1 (Suppl)
Critical events during intra-hospital transport of critically ill patients to and from intensive care unit
Vikas Saini, Qurram Pervez and Y L Narayana
Postgraduate Institute of Medical Education and Research, India
Statement of problem: Intra-hospital transport (IHT) of critically ill patients is frequently required for diagnostic or therapeutic
procedures that cannot be performed in Intensive Care Unit (ICU). In our hospital, five to seven patients per week are transferred from
the main ICU to operating room or for diagnostic procedures. Adverse events are common in both in- and out-of-hospital transports,
the most common being equipment malfunction. Studies have reported equipment problems and mishap in 11 to 34% of all transport
episodes. Research into this aspect of hospital care is lacking in our country. Knowledge about the potential complications associated
with IHT is essential to determine the safest way to transport patients reducing mortality and morbidity. This observational study was
designed to fill this epidemiological gap by determining the incidence and types of adverse events occurring during intra-hospital
transport of critically ill patients in a tertiary care hospital.
Aim: Aim of this study is to find the nature and rate of critical events occurring during intra-hospital transport of patients to and from
ICU and to formulate recommendations for prevention of critical events occurring during transport in future.
Methods: 160 consecutive IHTs of patients from ICU to procedure room or operation theater and back were prospectively studied
during an eight month period, from 1st October 2013 to 13th May 2014. A total of 248 critical events were observed in 104 IHTs
(65%; 95% Confidence Interval [95 CI] 57.4-72.1%). Critical events were divided into those related to the airway, monitors, drugs
and intravenous lines, equipment, cardiovascular system, respiratory system, and the procedure room, as well as miscellaneous ones.
Human glia expresses cytoglobin after brain trauma
Xiameng Chen1, Yuan Liu1, Haojie Qin2, Haibiao Zhu3, Yu Yang1 and Peng Guan1
1Sichuan University, China
2Henan University of Science and Technology, China
3China University of Political Science and Law, China
A190-amino acid protein-cytoglobin (Cygb) is a recently identified member of the vertebrate hemoglobin family. Cygb is an
ancient and highly evolutionarily conserved protein. Like the other members of the hemoglobin family, functions of Cygb
are mainly based on its oxygen binding ability. Cygb was previously demonstrated to be exclusively expressed by neurons of brain.
However, a recent research reported the expression of Cygb in human GBM cells, hinting that glia cells may also express Cygb under
certain pathological states. Therefore, to assess the cellular localization of human Cygb under physiological and pathological state, we
performed immuno-staining to post-mortem brain specimens from people who died of traumatic brain injury and deceased without
neuropathy, respectively. In uninjured human brains, the immuno-signal of Cygb was restricted in neurons but not glia cells whereas,
in the chronic brain trauma group, expression of Cygb was also detected in astrocytes and microglia cells in the injury repairing
area. Results of this present study offered the neuro-anatomical basis for further exploration of the neuroprotective role of Cygb and
suggested Cygb to be a novel therapeutic target in various neurological disorders.