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Volume 4, Issue 7(Suppl)

J Infect Dis Ther 2016

ISSN: 2332-0877, JIDT an open access journal

Skin Diseases & Microbiology 2016

October 03-05, 2016

Page 21

Notes:

conference

series

.com

Infectious Diseases, Diagnostic Microbiology &

Dermatologists Summit on Skin Infections

October 03-05, 2016 Vancouver, Canada

International Conference on

Acne and rosacea: Update on pathophysiology and treatment

U

nderstanding the pathophysiology of acne and rosacea is the basis not only for successful treatment but also for prevention

of recurrent disease. Acneiform lesions are due to blocked follicles (follicular plugging). This results in failure of drainage

of sebum to the skin surface and promotes accumulation of bacteria (

P. acnes

) and yeasts (

Pityosporum ovale

). The resultant

neutrophilic chemotaxis promotes the formation of microabscess, cysts and scarring. The follicular plugging is also aggravated

by sebaceous hyperplasia. In rosacea, cytokine-induced photosensitivity predominates with accompanying sebaceous

hyperplasia aggravating follicular plugging and pustule formation. Successful treatment of both diseases includes a regimen

aimed at unplugging the plugged follicles, control of pustule and abscess formation and resolution of acneiform scarring and

shrinkage of sebaceous hyperplasia.

Biography

Madalene C Y Heng is a Clinical Professor of Medicine, Dermatology at the David Geffen UCLA School of Medicine. From 1979 to 2003, she was a Chief, Division of

Dermatology, UCLA San Fernando Valley Medicine Program. She is currently in private practice in Heng Medical at Camarillo, CA and is a Reviewer for the

Journal

of the American Academy of Dermatology, American Journal of Geriatric Medicine, British Journal of Dermatology, Lancet, London, and International Journal of

Angiology.

She is the author of more than 140 scientific publications, including 78 published peer-reviewed articles on topics such as phosphorylase kinase activity

and psoriasis, pathophysiology of common skin diseases, and wound healing.

madalene@madalenehengmd.com

Madalene C Y Heng

David Geffen School of Medicine at UCLA, USA

Madalene C Y Heng, J Infect Dis Ther 2016, 4:7(Suppl)

http://dx.doi.org/10.4172/2332-0877.C1.016