Volume 4, Issue 7(Suppl)
J Infect Dis Ther 2016
ISSN: 2332-0877, JIDT an open access journal
Skin Diseases & Microbiology 2016
October 03-05, 2016
Page 21
Notes:
conference
series
.com
Infectious Diseases, Diagnostic Microbiology &
Dermatologists Summit on Skin Infections
October 03-05, 2016 Vancouver, Canada
International Conference on
Acne and rosacea: Update on pathophysiology and treatment
U
nderstanding the pathophysiology of acne and rosacea is the basis not only for successful treatment but also for prevention
of recurrent disease. Acneiform lesions are due to blocked follicles (follicular plugging). This results in failure of drainage
of sebum to the skin surface and promotes accumulation of bacteria (
P. acnes
) and yeasts (
Pityosporum ovale
). The resultant
neutrophilic chemotaxis promotes the formation of microabscess, cysts and scarring. The follicular plugging is also aggravated
by sebaceous hyperplasia. In rosacea, cytokine-induced photosensitivity predominates with accompanying sebaceous
hyperplasia aggravating follicular plugging and pustule formation. Successful treatment of both diseases includes a regimen
aimed at unplugging the plugged follicles, control of pustule and abscess formation and resolution of acneiform scarring and
shrinkage of sebaceous hyperplasia.
Biography
Madalene C Y Heng is a Clinical Professor of Medicine, Dermatology at the David Geffen UCLA School of Medicine. From 1979 to 2003, she was a Chief, Division of
Dermatology, UCLA San Fernando Valley Medicine Program. She is currently in private practice in Heng Medical at Camarillo, CA and is a Reviewer for the
Journal
of the American Academy of Dermatology, American Journal of Geriatric Medicine, British Journal of Dermatology, Lancet, London, and International Journal of
Angiology.
She is the author of more than 140 scientific publications, including 78 published peer-reviewed articles on topics such as phosphorylase kinase activity
and psoriasis, pathophysiology of common skin diseases, and wound healing.
madalene@madalenehengmd.comMadalene C Y Heng
David Geffen School of Medicine at UCLA, USA
Madalene C Y Heng, J Infect Dis Ther 2016, 4:7(Suppl)
http://dx.doi.org/10.4172/2332-0877.C1.016