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conferenceseries
.com
Volume 08
Journal of Community Medicine & Health Education
Public Health Summit 2018
May 24-25, 2018
May 24-25, 2018 Osaka, Japan
4
th
World Congress on
Public Health, Epidemiology & Nutrition
J Community Med Health Educ 2018, Volume 8
DOI: 10.4172/2161-0711-C2-036
The anti-diabetic use of
Allium cepa
(Garden Onions)
Desiree R Daniega
University of the Philippines, Philippines
O
ne of the natural products found to have anti-diabetic properties is
Allium cepa
, commonly known as garden onion.
Thus, this review paper will go through some researches which have been done to illustrate the anti-diabetic property
of
Allium cepa
. Quercetin, a major phenolic content in onion, inhibits the liberation of D-glucose from oligosaccharides
and disaccharides by inhibiting a-glucosidase, resulting in delayed absorption of glucose from the intestine and is thereby
considered responsible for controlling blood glucose levels. In several animal studies, the administration of oral juice of
Allium
cepa
significantly decreased the blood sugar levels in drug-induced diabetic rats. Ether extract of the fresh bulb, administered
to pancreatectomized dogs and rabbits by gastric intubation, was active. Ether extract of the fresh bulb, administered
intragastrically to rabbits at a dose of 250 gm/kg, was active. A dose of 10.0 mg/kg, administered orally to rabbits, was active.
A drop in blood sugar of 15 mg relative to inert treated controls indicated positive results. These results indicated that the
different extracts using different agents do not affect the activity of the anti-diabetic effects of the components of allium cepa.
Although, further studies have to be done in order to establish the most appropriate dosage for its maximal hypoglycemic
control without causing any harm to the animals of study,
Allium cepa
shows promising evidence as a possible food supplement
in the management of diabetes mellitus. Studies have demonstrated the potential benefit of
Allium cepa
in lowering the blood
sugar levels among drug-induced diabetic rats.
drdaniega@up.edu.ph