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Volume 8 J Community Med Health Educ, an open access journal
ISSN: 2161-0711 Public Health 2018
February 26-28, 2018
PUBLIC HEALTH AND NUTRITION
3rd World Congress on
February 26-28, 2018 London, UK
ALLERGEN SENSITIZATION AND VITAMIN D STATUS IN YOUNG KOREAN CHILDREN
WITH URTICARIA
Jung Won Yoona, Jeong Bong Leea , Shin Hae Leeb and Man Yong Hanb
aSeonam University College of Medicine, Myongji Hospital, South Korea
bCHA University, South Korea
Urticaria is a common disorder, with a lifetime incidence of approximately 15%–20% of the general population. It is difficult
to differentiate urticaria in children because of the similarity in symptoms between acute and chronic urticaria. There
is also a lack of studies between vitamin D known as an important role in the immune system and urticaria in children. The
present study aimed to assess the characteristics and allergen sensitization of young children diagnosed with urticaria and to
evaluate the relationship between their vitamin D status and urticaria.
We retrospectively reviewed medical records of 218 children diagnosed as having urticaria at CHA and Myongji Hospitals
between April 2013 and December 2014. The results of questionnaires and laboratory tests, including specific IgE and serum
25-hydroxy vitamin D concentrations were obtained.
Of 218 patients, 118 (54%) were positive for at least 1 allergen and there was no significant difference in the prevalence of
sensitization between the acute and chronic urticaria groups. However, the prevalence of polysensitization and sensitization
of house dust mites was significantly higher in the chronic urticaria group than in the acute urticaria group (P=0.011 and
P=0.029, respectively). Among the urticaria symptoms, an itching sensation was more associated with insufficient vitamin D
status in children with urticaria (P=0.034).
Our results demonstrated that children with chronic urticaria have a higher prevalence of sensitization to house dustmites and
polysensitization. Further studies will need to determine whether the supply of vitamin D can improve itching sensation in
urticaria children with an insufficient vitamin D status.
Biography
Jungwon Yoon has been graduated from INJE University, School of Medicine, as Medical Doctor with the specialties including Pediatrics, Respiratory and Allergy.
Later on, she obtained her post-graduation from CHA University School of Medicine with subjects “Useful Marker of Oscillatory Lung Function in Methacholine
Challenge Test - Comparison of Reactance and Resistance With Dose-Response Slope” and then started working at The Myongji Hospital, where she has been
continuing her research.
Jung Won Yoon et al., J Community Med Health Educ 2018, Vol 8
DOI: 10.4172/2161-0711-C1-032