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conferenceseries
.com
Volume 4, Issue 5 (Suppl)
J Pharmacovigil 2016
ISSN:2329-6887 JP, an open access journal
Pharmacovigilance Congress 2016
September 28-30, 2016
September 28-30, 2016 Toronto, Canada
6
th
Pharmacovigilance Congress
Min-Gyu Kang et al., J Pharmacovigil 2016, 4:5 (Suppl)
http://dx.doi.org/10.4172/2329-6887.C1.024Epidemiologic study based on Adverse Drug Events in patients visiting Emergency Department: A
retrospective Observational Study in Three University Hospital
Min-Gyu Kang
1
, Ju-Yeun Lee
3
, Tae-Ho Lim
4
, Byoung Whui Choi
2
, Chan-Woong Kim
5
, Baegeum Kim
3
, Ho Joo Yoon
6
, Sang-Heon Kim
6
,
and
Jae-Woo Jung
2
1
Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea
2
Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
3
College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Korea
4
Department of Emergency Medicine, Hanyang University College of Medicine, Seoul, Korea
5
Department of Emergency Medicine, Chung-Ang University College of Medicine, Seoul, Korea
6
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
Background
: Adverse drug events (ADE) has been recognized as an important cause of serious morbidity and mortality. Severe cases
of ADE requires immediate medical treatment including Emergency Department (ED) visits. However, the epidemiologic features of
ADE leading to ED visits have not been well described in Korea. We aimed to estimate the prevalence and features of ADE leading
to ED visits.
Methods
: In this retrospective observational study, we reviewed all the cases of ED visits for six months, from July 2014 to December
2014, in two university hospitals in Seoul and a university hospital in Cheongju in South Korea. By reviewing all the medical records
including National Emergency Department Information System Database, we identified cases of ADE and assessed the causative
drugs, severity, types and preventability.
Results
: The most common causative drugs of ADE was antineoplastic drugs, insulin and antidiabetic drugs, antithrombic or
antiplatelet agents and vaccines. In terms of system of clinical manifestations, gastrointestinal, skin, body as a whole, neurologic
and metabolic/nutritional symptoms were most frequent. The most common diagnoses of ADE were complication of insulin (and
antidiabetic drugs), complication of antithrombic (or antiplatelet) agents, dizziness, generalized skin rash, gastritis, and neutropenia
Conclusion
: The prevalence of ADE in ED visits was common Korea and higher in older adults and females. Many cases of ADEs
were preventable and predictable. Further prospective study is needed to evaluate the nationwide burden of ADE leading to ED visits.
Biography
Dr. Min-Gyu Kang is working at Chungbuk National University College of Medicine, Cheongju, Korea
irreversibly@gmail.com