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conferenceseries
.com
Volume 8
Journal of Biotechnology & Biomaterials
ISSN: 2155-952X
Pharma Biotech 2018
December 10-11, 2018
December 10-11, 2018 | Rome, Italy
23
rd
International Conference on
Pharmaceutical Biotechnology
Effect of a biosurfactant extract obtained from corn on probiotic bacteria
Alejandro López Prieto, Rodríguez-López L, Rincón-Fontán M, Cruz J M
and
Moldes A B
University of Vigo, Spain
Statement of the Problem:
Probiotics, prebiotics and nutraceuticals have been used over the years as supplements in several
treatments and control of diseases providing important health benefits. Among the probiotic bacteria,
Lactobacillus
casei
is
one of the most important. On the other hand, there are some bioactive compounds produced by lactic acid bacteria or
obtained from natural sources, with surfactant and antimicrobial pathogenic capacity, were named biosurfactants. These
biosurfactants could increase the effect of probiotics when added to pharmaceutical formulations improving their adsorption
and antimicrobial properties.
Aim:
The aim of this study was to establish the effect of a biosurfactant extract obtained from corn, which is able to reduce the
surface tension of water in more than 30 units, on the probiotic bacteria
Lactobacillus
casei
.
Methodology & Theoretical Orientation:
The biosurfactant extract was obtained from a corn milling industry stream by
liquid-liquid extraction with ethyl acetate. After extraction, ethyl acetate was evaporated obtaining a concentrated biosurfactant
extract that was added to an inoculum of
L. casei
at maximum concentrations of 0.5 g/L.
Findings:
It was observed that the addition of the biosurfactant extract obtained from corn had a positive effect on the biomass
of an inoculum of
L. casei
, maintaining and in some cases, favoring the growth of these probiotic bacteria, especially when this
strain was under optimal temperature conditions.
Conclusion & Significance:
This was the first study to assess the effect of a biosurfactant extract on probiotic bacteria. The
positive effect of the evaluated biosurfactant extract on
L. casei
growth could open the door to the application of biosurfactants
in pharmaceutical formulations although further studies will be necessary using other biosurfactants and probiotic bacteria.
Recent Publications
1. Banat I M, Makkar R S and Cameotra S S (2000) Potential commercial applications of microbial surfactants. App. Microb.
Biotech. 53(5):495-508.
2. Kaur I P, Chopra K and Saini A (2002) Probiotics: potential pharmaceutical applications. Eur. J. Pharma. Sci. 15(1):1-9.
3. Rodrígez-López L, Vecino X, Barbosa-Pereira L, Moldes A B and Cruz J M (2016) A multifunctional extract from corn
steep liquor: antioxidant and surfactant activities. Food Funct. 7(9):3724-3732.
Alejandro López Prieto et al., J Biotechnol Biomater 2018, Volume 8
DOI: 10.4172/2155-952X-C8-109