Volume 6, Issue 4(Suppl)
Pediat Therapeut 2016
ISSN: 2161-0665 Pediatrics, an open access journal
Page 64
Notes:
Pediatrics Conference 2016
September 14-16, 2016
conferenceseries
.com
7
th
European Pediatrics and
Pediatric Surgery
September 14-16, 2016 Amsterdam, Netherlands
Epidemiology and antimicrobial susceptibility of strains isolated from urinary tract infection outpatient
Elena Adela Brinzan
1
, M Nica
2
, C Strugaru
2
, D Popescu
1
, C P Popescu
2
, A Kosa
1
, G Gherlan
and
P Calistru
2
1
Dr V Babes Foundation
2
Carol Davila University of Medicine and Pharmacy, Romania
Aim
: Urinary tract infection (UTI) is the most common bacterial disease in children. The aim of this study was to compare the species
distribution and antimicrobial susceptibility pattern of strains isolated from outpatient pediatric with urinary tract infection.
Materials & Methods
: The study group consisted of children aged up to 12 years and lasted for two years (2014-2015). Organisms
were isolated using standard culture techniques. A total of 201 isolates were tested. The antibiotic susceptibility profiles were analyzed
for all strains using the Kirby Bauer disk diffusion susceptibility procedure and the VITEK 2 system for betalactam antibiotics,
fluoroquinolones, carbapenems, aminoglycosides, nitrofurans, sulfonamides, fosfomycin (CLSI 2014,CLSI 2015).
Results
: A total of 201 gram negative bacteria isolated from urine specimens, female infants were predominance.
Escherichia coli
154 isolates (76,6%) was the most common strain, followed by
Klebsiella
spp. 19 strains (9,45%),
Proteus
spp. 18 strains (8,95%). The
isolated bacteria were
Escherichia coli
(76,6%); 18 cases (11,6%) were found to be ESBL-producing organisms.
E. coli
isolates ESBL-
producing were susceptible to carbapenems, nitrofurans, amikacin, fosfomycin. The large majority of
E. coli
strains were resistant to
ampicilin. All isolates
Klebsiella
spp. and
Proteus
spp. were susceptible to carbapenems, phosphomycin and amikacin.
Conclusions
:
Escherichia Coli
was the most common causative organism for pediatric UTI. Recurrent episodes of UTI was presented
a risk of ESBL-producing and antimicrobial resistance. The majority of ESBL isolates were susceptible to carbapenems, phosphomycin
and amikacin, these antibiotics were important therapeutic options for infections due to multidrug-resistant.
Biography
Elena Adela involved under treatments of pediatric diseases she is belongs to Pediatrics, Dr V Babes Foundation. Elena Adela educational institution is the University of
Medicine and Pharmacy “Iuliu Hatieganu” Cluj Napoca, Faculty of Medicine. She finished her postgraduate training courses. Cardiopulmonary resuscitation and pediatric
cerebral”, organized by the Romanian National Council for Resuscitation, University of Medicine and Pharmacy.
brinzanadela@yahoo.comElena Adela Brinzan et al., Pediat Therapeut 2016, 6:4(Suppl)
http://dx.doi.org/10.4172/2161-0665.C1.034