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conferenceseries.com
September 25-26, 2017 Chicago, USA
3rd International Conference on
Parkinson’s disease and Movement Disorders
Volume 7, Issue 5 (Suppl) J Alzheimers Dis Parkinsonism, an open access journal
ISSN: 2161-0460 Parkinson 2017
September 25-26, 2017
Motor sensory stimulation (Modulation) in Parkinsonism
Parkinsonism is a neurodegenerative disorder characterized by a progressive loss of midbrain dopaminergic (DA) system.
Subsequent reduction in striatal dopamine results in various clinical manifestations with Tremor, Rigidity, Bradikinesia and
Postural defect. The term Motor Sensory stimulation (Modulation) encompasses a broad range of treatments, both electrical
and chemical, targeting various locations in the Brain and the body to achieve the desired results. Deep brain stimulation (DBS)
is a Neurosurgical treatment used in Parkinsonism and other conditions. Electrical stimulation at high frequency in precise
locations of the brain results in the restoration of the balance of the circuits that are disrupted in Parkinsonism (Parkinson
Disease). Stimulation in high frequency of the sub thalamic nucleus has now become a standard Neuro Surgical therapy in
Parkinson disease. Transplantation of fetal dopaminergic (DA) neurons also produces symptomatic relief. The technical and
ethical difficulties in obtaining sufficient and appropriate donor fetal brain tissue are the limitations in the application of this
therapy. Neural precursor cells and embryonic stem (ES) cells are going to be the potential donor cells for
the mid-1990s, creation of targeted holes in specific areas of the brain or Lesioning were the main approaches.Repalement Cell
therapy was tried in some cases. Transcranial Magnetic Stimulation (TMS) is a non-invasive way of stimulating the brain, have
also shown benefit in Posture and gait in some patients of Parkinson Disease. This targeted Stereotactic thalamotomy of the
thalamic nucleus ventralis intermedius (VIM) is routinely used for bilateral extrapyramidal movement disorders. This targeted
neuromodulator therapies can avoid the side effects. They are easily reversible if and when occurs, they can give an important
degree of therapeutic effect in patients. This communication addresses the mainly Deep Brain Stimulation,Transplantaion and
Stem Cell therapy and its Frontiers of the Neurophysiological basis,technical,ethical considerations and its Therapeutic effects
in Parkinsonism, Tremor and Dystonia patients.
Biography
Srinivas Avathvadi Venkatesan is the President of Indian Academy of Neurology and also he is the emeritus Professor of The Tamilnadu DR.M.G.R.Medical
University. Srinivas Avathvadi Venkatesan, driven by his quest for excellence and the latest discoveries on human brain related disorders, joined Madras Medical
College (MMC) and received MD(General Medicine) in 1978.Later he pursued and received DM in Neurology from his alma is First Neuro physician of his
state Tamil Nadu in India in government service to be conferred, the Fellow of the Royal College of Physicians (FRCP) in London in 2012, fellowship of the Indian
Academy of Neurology 2004 and fellowship by the American Academy of Neurology, in Is the First Indian to receive American Indian Neurology Award
(AINA) in USA in 2001, for the best paper presentation IN STROKE during annual American Academy of Neurology meeting in 2001 in PHILADELPHIA. ByTheT-
amil Nadu DR. MGR Medical University. Currently serving as a Member –in the ACADEMIC COUNCIL of National institute of Mental health and Neurosciences,
Deemed University, Bangalore.
Srinivasan Avathvadi Venkatesan
DR.M.G.R.Medical University, India
Srinivas Avathvadi Venkatesan, J Alzheimers Dis Parkinsonism 2017, 7:5 (Suppl)
DOI: 10.4172/2161-0460-C1-030