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Pain Management 2016
October 03-04, 2016
Volume 5, Issue 5(Suppl) J Pain Relief
ISSN: 2167-0846 JPAR, an open access journal
conferenceseries .com
October 03-04, 2016 Vancouver, Canada
International Conference on
Pain Research & Management
Hossam El Beheiry, J Pain Relief 2016, 5:5(Suppl)
Uses and abuses of opioids for chronic non-cancer pain
Hossam El Beheiry
University of Toronto, Canada
Non-cancer chronic pain is pain lasting longer than three months or past the normal time for tissue healing not related to
malignancy (Neurology 83:1277-84, 2014). Non-opioid medications were the only class of analgesics that was used for
managing these conditions until the later part of 1990s. Following the recommendation of various medical authorities, various
opioid compounds were used for the long termmanagement of non-cancer chronic pain. However, such development resulted
in an exponential increase in the number of prescriptions of opioids as well as an increase in the incidence of side effects and
overdose related to these potent drugs. Over the last two decades, many studies particularly in the last five to seven years
have been performed to investigate the efficacies and side effects of opioid therapy for non-cancer chronic pain. The purpose
of this paper is to review such studies including systematic reviews, discuss the recent Canadian guidelines and evaluate the
occurrence of side effects in addition to overdose and risks of long-term therapy. All relevant articles in the last five years were
reviewed pertaining to the effectiveness, side effects and abuses, dosing strategies and risk assessment of opioid therapy for
non-cancer chronic pain (Ann Int Med 162:276-86, 2015). The preliminary results of the review showed an equivocal evidence
for long term effectiveness of opioid medications to control chronic non-cancer pain. Additionally, the preliminary results
support the notion that long term opioid administration is associated with dose-dependent risk for serious side effects and
abuses.
Biography
Hossam El Beheiry has obtained his Anesthesia FRCPC Specialty Certificate in Anesthesia in the year 1994. In 1990, he completed his PhD from the Department
of Pharmacology and Therapeutics, the University of British Columbia, Canada. He has also spent a year as a Fellow in Clinical Pharmacology at the University
of British Columbia. He is a trained Neuroanesthesiologist at the University of Toronto, Canada. He has authored many publications in Opioid Pharmacology and
Regional Anesthesia including complications of Regional Nerve Blocks.