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conferenceseries.com
Ophthalmology 2016
November 21-23, 2016
November 21-23, 2016 Dubai, UAE
10th International Conference on
Clinical & Experimental Ophthalmology
Volume 7 Issue 9 (Suppl) J Clin Exp Ophthalmol
ISSN: 2155-9570 JCEO, an open access journal
Poonam Lavaju et al., J Clin Exp Ophthalmol 2016, 7:9(Suppl)
Autologous serum eye drop in refractory neurotrophic corneal ulcer: A case report
Poonam Lavaju, Shah S, Joshi I and Pant A R
BP Koirala Institute of Health Sciences, Nepal
Introduction: Refractory neurotrophic corneal ulcer is a degenerative disease characterized by decreased corneal sensitivity,
spontaneous epithelium breakdown, and impairment of corneal healing which are nonresponsive to multitude of medical treatment.
Case Description: A 20-year- old-male presented with a history of sudden onset redness and foreign body sensation of both eye since
3 months associated with photophobia and progressive diminution of vision of both the eyes (RE>LE) since 2 months. He also gave
history of oral ulcers 3 months back followed by frequent episodes of dry mouth. On examination, the best corrected visual acuity
(BCVA) in RE was 1/60 and LE 6/12. Blepharospasm was present in the both eyes (OU). There was presence of posterior blepharitis
and thickening of the eyelid margins and keratinization, bilateral conjunctival xerosis and diffuse ciliary congestion OU. RE cornea
showed epithelial defect of 4.5x1.5 mm with thinning (~80%) and LE had diffuse SPKs. Corneal sensation was decreased with
Schirmer’s test I reading of 1 mmOU. Anterior segment and fundus examinations were within normal limits in both eyes. Provisional
diagnosis of refractory neurotrophic corneal ulcer was made and autologous serum eye drops (20%) was started in RE 4 hourly along
with topical preservative free tear substitutes and weak steroids in both the eyes. The patient showed dramatic improvement in signs
and symptoms within one week of initiation of treatment.
Conclusion: Management of refractory neurotrophic corneal ulcer is a challenge for ophthalmologists. Autologous serum eye drops
can be useful in such cases and may prevent further complications.
Biography
Poonam Lavaju is currently working as an Additional Professor in the Department of Ophthalmology at BP Koirala Institute of Health Sciences, Dharan, Nepal. She
is involved in academics program for undergraduate and post graduate students in ophthalmology. She is In-Charge of the Department. She has published articles
in index journals both in national and international journals. She is one of the Board Members in Nepal Eye Bank Committee.