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Volume 8

Journal of Obesity &Weight Loss Therapy

Obesity Summit 2018

July 10-11, 2018

July 10-11, 2018 Bangkok, Thailand

World Obesity Congress

Cocoa supplementation has beneficial effects on plasma High Density Lipoproteins cholesterol (HDLc)

and triglyceride in central obesity male with atherogenic dyslipidemia, but no significant changes on

oxidized Low Density Lipoproteins (LDL)

Syaiyed Jamaluddin

Hasanuddin University, Indonesia

Background:

Central obesity related to atherogenic dyslipidemia which was characterized by high serum triglycerides,

increased sLDL and decreased HDLc. Cocoa powder rich in polyphenols as antioxidant sources reduced atherosclerosis risk.

Objective:

To investigate the influence of cocoa supplementation to atherogenic dyslipidemia in central obesity male subjects

by assessing lipid profiles and oxidised LDL.

Method:

34 healthy males (aged >25-55 years, waist >90 cm) were recruited to participate in an 8-week randomized, paralel

and double-blind study: 17 subjects received 4-gram cocoa in capsules and the other 17 subjects received placebo. Both groups

had 15% energy restriction and fat <25% of total energy, no changes in activities.

Results:

After 8 weeks, no changes in total cholesterol and triglycerides in both groups (p >0.05). LDLc level decreased

significantly in both groups (cocoa p=0.003 vs. placebo p=0.004,). HDLc level increased significantly only in cocoa group

(p<0.05) and oxidized LDL level showed no changes in both groups (p>0.05). If we compared atherogenic cocoa group with

atherogenic placebo group (n=17), we found no changes in total cholesterol in both groups (p>0.05), but higher reduction in

triglyceride showed in atherogenic cocoa group p=0,043). HDLc level increased significantly only in atherogenic cocoa group

(p=0.011), no changes in atherogenic placebo group (p=0.575). Oxidized LDL level showed no changes in both atherogenic

groups (p>0.05).

Conclusion:

Cocoa supplementation on central obesity male within a hypocaloric and low-fat diet increased HDLc in

dyslipidemia and atherogenic dyslipidemia, higher reduction in triglyceride in atherogenic dyslipidemia then placebo. No

significant changes showed in oxidized LDL level in both dyslipidemia and atherogenic dyslipidemia.

J Obes Weight Loss Ther 2018, Volume 8

DOI: 10.4172/2165-7904-C4-067