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Volume 7, Issue 6 (Suppl)
J Obes Weight Loss Ther
ISSN: 2165-7904 JOWT, an open access journal
Obesity Meeting 2017
October 23-24, 2017
October 23-24, 2017 Dubai, UAE
14
th
Global Obesity Meeting
Effect of probiotic consumption in the level of peptide YY, ghrelin hormone and body weight in Iraqi
obese female
Fakhri Alajeeli
Tikrit University, Iraq
Background:
Several evidences indicate that gut microbiota is involved in the control of host energy metabolism.
Objective:
To evaluate the change of body weight and hormone level after consumption of probiotics for 8 weeks.
Methods:
40 healthy obese female age between (20-50) years and BMI ≥30 (kg/cm) was participated in this study, there were
divided in two groups, group-1 (G1) consumed probiotics and group-2 (G2) was consumed placebo for 8 weeks, the two
groups was used same diet with 1200 kcal. The body weight was determined at the first of study and after 8 weeks, the level of
ghrelin and peptide YY was de-terminated by using ELISA technology.
Result:
The study show significant effect of probiotic on the peptide YY hormone level and showed positive correlation with
body weight. The study showed highly significant difference in the level of peptide YY hormone, the peptide YY hormone level
was increased in the G1 from (33.7) to (49.5) with (p-0.0001) compared with G2 which showed decreasing by 1.4% from (33.62)
to (32.62). The study showed significant difference between two groups in the level of ghrelin, G1 it was decreased from (6.67)
to (2.17) but in the G2 increased from (5.87) to (7.0). Effect of probiotic on the body weight was study to determine the role of
probiotic in weight reduction and the result showed difference between two groups. The group (G1) showed decrease (5.4%)
5.4 kg from (92.92) to (87.88) and G2 showed decreased 4.14% (3.4) kg from (91.28) to (87.5) but there was no significant
difference between two groups.
Conclusions:
The study show positive effect of probiotics on the hormone level and body weight more study need to evaluate
the probiotics effect on endocrine system.
fakhry_lab_2005@yahoo.comJ Obes Weight Loss Ther 2017, 7:6 (Suppl)
DOI: 10.4172/2165-7904-C1-052