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conferenceseries
.com
Volume 7, Issue 5
J Nov Physiother, an open access journal
ISSN: 2165-7025
Novel Physio 2017
August 21-22, 2017
4
th
International Conference and Expo on
August 21-22, 2017 | Birmingham, UK
Novel Physiotherapies
J Nov Physiother 2017, 7:5(Suppl)
DOI: 10.4172/2165-7025-C1-018
Comparing the effect of intensive conventional intervention versus modified constraint-induced
movement therapy in stroke patients with upper extremity spasticity following a botulinum-a toxin
injection: A randomized controlled trial
M Nasb
Jilin University, China
Introduction:
Stroke, the second leading cause of mortality around the globe is also one of the main causes of adult disability,
which significantly decrease their quality of life. Thus, it attracted various intense researches to overcome this issue and
culminated in development of therapeutic approaches. Botulinum-A toxin injection combined with other rehabilitation
method such as modified constraint-induced movement therapy (BTX-mCIMT) emerged as highly promising intervention
for stroke therapy. This is ascribed to achieving faster functions restoration, better toleration, and prompt efficiency. It should
be noticed that, the BTX-mCIMT and Botulinum-A toxin injection intensive conventional intervention (BTX-T) comparison
has not been systematically highlighted previously in the literature. In pursuit of this aim, the present study is dedicated to
compare between the BTX-CIMT and BTX-T in post stroke patients.
Objective:
The present study is dedicated to determining whether there are any differences in therapeutic effects of BTX-
mCIMT and BTX-T on stroke patients with upper extremity impairment, to explore the best way to facilitate motor recovery
in stroke.
Methods:
58 cases of stroke were recruited from department of rehabilitation center of the first hospital of Jilin University from
February 2014 to November 2016, the age was between 10 and 70 years old, onset time from 2 weeks to 12 months. Total 32
participants met the inclusion criteria, then all of them had the injection of BTX-A. Later, they were randomly divided into two
groups: intensive conventional rehabilitation therapy (BTX-T), and modified constraint-induced movement therapy group
(BTX-mCIMT). Both groups had the therapy for 1 hour a day, 5 days a week and for 4 weeks. Motor function was assessed
by the modified Ashworth scale (MAS), Fugl-Meyer Assessment of the upper extremity (FMA), and Barthel index (BI) before
treatment and 4 weeks after treatment.
Results:
After 4-week treatment, both groups revealed a significant improvement in MAS, FMA and BI score compared with
pre-treatment’s (p<0.05). BTX-mCIMT group possessed a noteworthy higher mean score in FMA and BI (the mean score
of 52 and 77.6 respectively) than BTX-T group’s (the mean score of 37.5 and 70 respectively) (P<0.05) at the end of 4 weeks’
treatment, however, no significant statistical difference was seen in MAS score (P>0.05).
Conclusion:
Both BTX-mCIMT and BTX-T can facilitate motor function recovery in stroke. Compared with BTX-T, BTX-
mCIMT shows better curative effects on motor function recovery and daily living ability.
mmn87@yahoo.com