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conferenceseries
.com
Volume 6, Issue 6 (Suppl)
OMICS J Radiol, an open access journal
ISSN: 2167-7964
Neuroradiology 2017
October 30 to November 01, 2017
October 30 to November 01, 2017 | San Antonio, USA
2
nd
International Conference on
Neuroscience, Neuroimaging & Interventional Radiology
Mechanical thrombectomy for pediatric acute ischemic stroke review of the literature and treatment
algorithm
Sudhakar R Satti
Christiana Care Health System, USA
Objective:
In light of the recent strongly positive randomized controlled adult mechanical thrombectomy trials, we sought to review
the available literature and perform a meta-analysis on intra-arterial pediatric stroke intervention with a focus on modern mechanical
devices.
Methods:
A PubMed search was performed for pediatric patients undergoing intra-arterial treatment of acute ischemic stroke using
modern devices between 2008 and 2015. A total of 29 patients were included in this retrospective meta-analysis.
Results:
The average age was 10.3 years old, 74.1% were male, the middle cerebral and basilar arteries accounted for 89.6% of 36
occluded vessels and the average pediatric stroke scale score was 18.1. The average time from symptom onset to intervention was
8.8 hours and 13.8% of patients received IV tPA prior to mechanical thrombectomy. Stent retrievers were used in 58.6% of cases, the
Penumbra system in 34.5% and the Merci device in 27.6%. TICI 2b/3 recanalization was achieved in 75.9% of cases. There were no
major adverse events related to intervention, although 1 procedure was associated with device malfunction, without definite change
in long term outcome. The average mRS was <1 (0.86) at the longest available follow-up period, based on clinical description or
provided modified Rankin scale score.
Conclusions:
This study suggests mechanical thrombectomy in pediatric patients presenting with high pediatric NIHSS scores
and proximal large vessel occlusion is associated with high recanalization rates and excellent clinical outcome, although this is a
retrospective review and sample size is too small to make any definitive conclusion.
ssatti@christianacare.orgOMICS J Radiol 2017, 6:6, (Suppl)
DOI: 10.4172/2167-7964-C1-019