neurology-congress-2016_scientifictracks-abstracts

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Volume 7, Issue 4 (Suppl) J Neurol Neurophysiol
ISSN:2155-9562 JNN, an open access journal
Page 55
Notes:
Neurology Congress 2016
September 21-23, 2016
conferenceseries.com
September 21-23, 2016 Amsterdam, Netherlands
8th European Neurology Congress
Prenatal stress potentiates febrile seizure in human offspring
Sedra Mohammadi1, EhsanSaboory1, Peyman Gholipoor2, Ahad Ghazavi1, Arezoo Kiyani1 and Shiva Roshan-milani1
1Urmia University of Medical Science, Iran
2Tabriz University of Medical Sciences, Iran
Introduction & Aim: A febrile seizure is a neurological disorder that occurs following an infection that results in a rapid rise in
body temperature. It commonly affects 3–5% of children between the ages of 3 months and 5 years. There is evidence suggesting
that neurological disorders can be exacerbated in an offspring that was exposed to stress prenatally. This study aimed to investigate
severity of febrile seizures in prenatally stressed offspring.
Method: In the current study, 158 children under 2 years old with febrile seizure were selected. Information about convulsion
including seizure lasting, recurrence of seizure, age of first seizure and type of febrile seizure (simple or complex) were obtained.
Questionnaire to evaluate the perceived stress and exposure to major stress during pregnancy was completed.
Results: This finding showed that both high score of perceived stress and exposure to major stress during pregnancy significantly
increased seizure lasting and seizure intensity. Exposure to prenatal stress did not have any significant effects on recurrences of febrile
seizure and on age of onset of first febrile seizure. Also, appearance of complex febrile seizure was significantly higher in children born
from mothers with major-stress exposure compared to unexposed one.
Conclusion: This study indicated that there is a significant positive relationship between both higher perceived stress score and
exposure to major stresses during pregnancy with seizure parameters in offspring.
Biography
Sedra Mohammadi is pursuing her Medicine from the Urmia University of Medical Science. She is a Member of Student Research Committee of Urmia University
of Medical Science since 2014. She has published 2 papers in journals and has been serving as a Redactor of Scientific Journal of Student Research Committee.
Sedra Mohammadi et al., J Neurol Neurophysiol 2016, 7:4 (Suppl)