neurology-congress-2016_scientifictracks-abstracts

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Volume 7, Issue 4 (Suppl) J Neurol Neurophysiol
ISSN:2155-9562 JNN, an open access journal
Page 54
Notes:
Neurology Congress 2016
September 21-23, 2016
conferenceseries.com
September 21-23, 2016 Amsterdam, Netherlands
8th European Neurology Congress
Involvement of the fronto-temporal network in the pathogenesis of auditory hallucinations: Insights from
Neuroimaging and Neuromodulation
Frederic Haesebaert
University of Lyon, France
Auditory hallucinations (AH) are common and disabling symptoms of schizophrenia. Despite prescriptions including adequate
pharmacological treatments, about 25% of patients still experience refractory AH symptoms. This epidemiological fact supports
the urge need of understanding AH and developing new treatment strategies. Indeed, the patho-physiology of AH is complex and
still partially unelucidated. In clinical terms AH correspond to "true" auditory perception in the absence of an auditive stimulus. In
a neuropsychological perspective, they are commonly related to a lack of cognitive control over the hearing function. This lack of
control leads to perception of self generated events misattributed to someone else. We present here key findings on brain networks
supporting hearing and speech perception involved in the pathogenesis of AH symptoms, drawing perspectives for new treatments.
Indeed, our team’s research includes studies at the clinical, neuropsychological and neurophysiological level highlighting the role of
fronto-temporal networks in AH generation. First we will briefly review data of the literature assessing the involvement of temporal
and frontal lobes in AH and their pathological interactions with other brain structures in schizophrenic patients with AH. Then
we will show how trans-cranial current brain stimulations (tCS) of fronto temporal network can induce a clinical reduction of AH.
Finally we will focus on the mechanisms of action of AH improvement with tCS, investigating biological markers of response.
Biography
Frederic Haesebaert has completed his MD in 2010, and his PhD in 2013 at the age of 33 years from Lyon University. He is now the head of a department of
neuromodulation in psychiatry dedicated to treatment resistant pathologies, in Lyon, and also a reseacher investigating the mechanisms of action of Non Invasive
Brain Stimulations (NIBS) in psychiatric populations. He has published more than 10 papers in reputed journals and is the author of book chapters and confrences
in this field of psychiatry and neuromodulation.
Frederic Haesebaert, J Neurol Neurophysiol 2016, 7:4 (Suppl)