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Volume 6, Issue 3 (Suppl)

J Neonatal Biol, an open access journal

ISSN:2167-0897

Neonatology 2017

December 04-06, 2017

December 04-06, 2017 | Madrid, Spain

International Conference on

NEONATOLOGY AND PERINATOLOGY

Unusual presentation of cow milk protein allergy in a neonate

Jamie Alexander Grech, Pace K, Mizzi C

and

Shoukry M

Mater Dei Hospital, Malta

Cow’s Milk Protein Allergy (CMPA) represents the majority of food allergies in children, especially in early childhood, with an

incidence of up to 3% in the first year of life. Indeed, 90% of patients develop CMPA before they reach 3 months of age and often

within a week of introducing cow’s milk protein into their diet. Classical presentation may involve variable gastrointestinal

symptomatology, inclusively regurgitation, vomiting, diarrhoea or constipation, among other non-gastrointestinal signs and

symptoms. We report an unusual presentation of CMPA in a previously healthy eight day old formula fed baby girl, who was

admitted due to multiple episodes of vomiting followed by a single instance of bile-stained vomiting associated with maroon-

coloured blood stained stools on the first day of admission. Physical examination was non-remarkable. Initial diagnostic

investigation included a water-contrast upper gastrointestinal tract study with follow-through and delayed films, to exclude

mid-gut malrotation as sinister surgical pathology. Elimination of ominous pathologies from the differential diagnosis and

cessation of symptoms with interruption of formula feeds led to a working diagnosis of CMPA. Reintroduction of hypo-allergic

formula feeds elicited no relapse of symptoms, and the patient improved dramatically, further supporting this diagnosis. High

index of suspicion is mandatory in management of such challenging cases.

Biography

Jamie Grech completed undergraduate medical education at the University of Malta in 2016, before completing a Postgraduate Certificate in Child Welfare and

Wellbeing from Oxford Brookes University. He is currently reading for a Master of Science degree in Neonatal Medicine at Cardiff University while undergoing

Foundation Programme training at Mater Dei Hospital, Malta.

kristyna.zilinska@ftn.cz

Jamie Alexander Grech et al., J Neonatal Biol 2017, 6:3(Suppl)

DOI: 10.4172/2167-0897-C1-006