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Volume 6, Issue 3 (Suppl)
J Neonatal Biol, an open access journal
ISSN:2167-0897
Neonatology 2017
December 04-06, 2017
December 04-06, 2017 | Madrid, Spain
20
th
International Conference on
NEONATOLOGY AND PERINATOLOGY
Gastric aspirate shake test in preterm neonates to predict respiratory distress syndrome
Satish Koirala
Kathmandu Medical College, Nepal
Introduction:
Respiratory Distress Syndrome (RDS) is a major cause of mortality and morbidity in preterm babies. Early
prediction of RDS is vital in the management of preterm babies. Among the various test, the gastric aspirate shake test is a
simple bedside test to predict RDS.
Objective:
To evaluate whether the shake test performed in the gastric aspirate sample in preterm babies can predict the
likelihood of respiratory distress syndrome of prematurity.
Methods:
A prospective hospital-based cohort study conducted at the NICU of Kathmandu Medical College for 6 months
fromMay to October 2014. All live born babies greater than or equal to 26 weeks and less than 37 weeks (36+6) gestation were
included in the study. Neonates who could only be seen after 1 hour of life, neonates in whom gastric aspirate samples < 0.5
ml were obtained or those samples mixed with blood or meconium, neonates who were fed before the procedure, neonates
with severe congenital anomalies incompatible with life and those with parents denying to give consent were excluded from
the study. Babies were defined to have respiratory distress syndrome if the neonate develop any two of the clinical signs of
respiratory rate > 60/min, expiratory grunting, suprasternal, intercostal retraction or cyanosis within 6 hrs of life and persisted
for >24 hours with chest xray showing hypoaeration, diffuse reticulogranular pattern with air bronchogram. The shake test
results were read as positive ( if complete rim of bubbles were present across the surface of the fluid), intermediate ( an
incomplete rim of bubbles were present across the surface of the fluid), negative ( if no bubbles were seen). The results of the
shake test were then compared with clinical diagnosis of neonatal respiratory distress syndrome.
Results:
Among the 50 preterm babies who were enrolled in the study, 15 (30%) babies developed RDS. Similarly, shake test
predicted 48% as mature (positive shake test) and 34% intermediate and 18% as immature (negative shake test). The sensitivity,
specificity, positive predictive value (immaturity), negative predictive value (maturity) by shake test was 93.3%, 65.7%, 53.8%
and 95.8% respectively.
Conclusions:
Gastric aspirate shake test in preterm babies is a simple yet reliable test for prediction of fetal lung maturity and
therefore can be used routinely in resource limited settings to predict RDS.
skoirala_2009@hotmail.comJ Neonatal Biol 2017, 6:3(Suppl)
DOI: 10.4172/2167-0897-C1-006