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Volume 6 Journal of Infectious Diseases & Therapy-Open Access Infectious Diseases Congress 2018
November 15-16, 2018
November 15-16, 2018 Istanbul, Turkey
6th Annual Conference on
Parasitology & Infectious Diseases
Ozer Akgul et al., J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C5-050
High association of intestinal parasites with cancer and organ transplant recipient patients in Turkey
Ozer Akgul1, Reyhan Caliskan1, Yasar Ali Oner1, Ayse Canan Yazici Guvercin1 , Hayriye Kirkoyun Uysal2, Ozgur Kurt3 and Ilker Tosun4
1Istanbul Aydın University, Turkey
2Istanbul University, Turkey
3Acıbadem Mehmet Hospital, Turkey
4Acıbadem Bodrum Hospital, Turkey
In healthy individuals, intestinal parasitic infections generally self-limiting, but it may cause severe complications such
as persistent diarrhea and/or malabsorption in patients with immune compromising conditions (such as, undergoing
chemotherapy, organ transplantation and AIDS). Hence, the main aim of this case-control study was to detect the intestinal
parasites (Cryptosporidium spp., Giardia spp., Entamoeba histolytica, Blastocystis spp. and Dientameba spp.) with microscopic
and molecular methods among the immune compromised group consisting of Cancer Patients (CP) and Organ Transplant
recipient Patients (OTP) in comparison with Healthy Individuals (HI) in Turkey. The present study was conducted among
90 HI and different groups of immune compromised patients, including 57 CP and 33 OTP in Turkey. The overall frequency
of any intestinal parasites was 17.2% (31/180) with microscopy and 51.7% (93/180) with PCR technique. The presence of
intestinal parasites in CP was 24.6% (14/57) and 80.7% (46/57), in OTP was 18.2% (6/33) and 57.6% (19/33), in HI was 12.2%
(11/90) and 31.1% (28/90) with microscopy and PCR techniques, respectively. Also, all parasite species were shown in Table 1
(p<0.001). Table 2 was shown data that in the detection of parasites, the accuracy of the microscopy technique was analyzed
in comparison to that of the PCR technique (p<0.001) (Table 2). This is the first study performed in Turkish reporting the
prevalence of 5 intestinal parasites among these groups. These results show that Cryptosporidium spp. and multiparasitism are
strongly associated cancer patients but, further studies are needed to reach definitive conclusions about this association.
Biography
Ozer Akgul has completed his PhD from Department of Medical Microbiology at Istanbul University and Postdoctoral studies from Istanbul Aydin University School
of Medicine. He is currently working as Assistant Professor at Istanbul Aydin University School of Medicine. He has published more than 10 papers in reputed
journals and has been serving as an Editorial Board Member.