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Volume 5, Issue 7 (Suppl)

J Infect Dis Ther, an open access journal

ISSN: 2332-0877

Infection Prevention 2017

December 14-15, 2017

December 14-15, 2017 | Rome, Italy

World Congress on

INFECTION PREVENTION AND CONTROL

Detectionof the

mcr-1

colistin resistance gene and extended-‎

spectrumbeta-lactamase (esbl)-producing

Escherichia coli

from ‎

poultry in Qatar

Nahla Eltai

Qatar University, Qatar

ntimicrobial resistance (AMR) is a growing public health concern worldwide and is one of the top health challenges

facing humanity in the 21st century. AMR among

Enterobacteriaceae

is rapidly increasing especially to third-generation

cephalosporins and carbapenems. Further, strains carrying mobilized colistin resistance (mcr) genes 1 & 2 have been isolated

from humans, food-producing animals, and environment. Uncontrolled use of antibiotics in animals in large scale could

be one of the major contributing factors to generation and spread of antibiotic resistance. No studies have been done to

evaluate antimicrobial resistance in animals in Qatar. This study aimed at establishing a primary baseline data for prevalence

of antimicrobial resistance among food animals in Qatar. 172 fecal samples were obtained from two broiler farms and one live

bird market in Qatar and 90

Escherichia coli

(

E. coli

) bacteria were isolated and subjected to antimicrobial susceptibility testing

using E test method. 90% (81/90) of the isolates were resistant to at least one of the 16 tested antibiotics. 15.5% (14/90) of the

isolates were colistin resistant, 2.2% (2/90) were extended spectrum β lactamase (ESBL) producers and similar percentage were

multi-drug resistant (MDR) to four antibiotic classes. ESBL-producing E. coli and colistin resistant isolates were confirmed

using double disc susceptibility testing and PCR, respectively. In summary, our results indicate high antimicrobial resistance

in food producing animals in Qatar, including ESBL and colistin resistance. Such AMR bacteria could be easily transmitted

to humans through consumption of undercooked food or noncompliance with hygiene practices, which mandates prompt

development and implementation of stewardship program to control andmonitor the use of antimicrobial agents in community

and agriculture.

J Infect Dis Ther 2017, 5:7(Suppl)

DOI: 10.4172/2332-0877-C1-036