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Volume 8 Gynecology & Obstetrics
ISSN: 2161-0932 Gynecology 2018
October 08-10, 2018
October 08-10, 2018 | Zurich, Switzerland
5th International Conference on
Gynecology and Obstetrics
Blood type and postpartum hemorrhage
Mais Ali-Saleh
Carmel Medical Center, Israel
Background &Aim: Early postpartum hemorrhage is the leading cause of maternal mortality. The most common cause of early
postpartum hemorrhage is uterine atony, but coagulation disorders can also lead to heavy bleeding. Von Willebrand disease,
for example, is a common inherited condition that arises from a deficiency in the quality or quantity of Von Willebrand factor
(VWF). Many studies have reported that ABO blood type system has an important effect on hemostasis, mainly by determining
the level of VWF and indirectly determining the level of factor VIII in the blood. A, B and AB blood group individuals have
VWF levels approximately 25-30% higher than O subjects. While a number of studies have analyzed the relationship between
ABO blood groups and vascular thrombosis, only a few studies have been published on the association between ABO blood
groups and hemorrhagic disorders. The aim of this study was to explore whether blood type O is associated with an increased
risk for early postpartum hemorrhage compared to the other blood groups.
Methods: Data were collected for women who gave birth at Carmel Medical Center in Haifa between December 1, 2014 and
March 3, 2016. Women were categorized according to blood type as O and non-O blood groups. The study included women at
the age of 20-45 who gave birth at 34-42 weeks of gestation. Women with known coagulation disorders, unknown blood type
and intrauterine fetal death were all excluded. The primary outcomes were defined as early postpartum hemorrhage and blood
transfusion. The comparison of categorical variables was done using the χ2 or Fischer’s exact test, whereas the comparison of
the continuous variables was done using student's t-test or ANOVA. The relevant data were further processed using a stepwise
logistic regression model. P<0.05 values were considered statistically significant.
Results: 4,516 women were included in the study, of which 1,594 (35.3%) were found to have blood type O. After multivariate
analysis, blood type of the parturient was not associated with an increased risk for early postpartum hemorrhage and/or with
packed red cells transfusion (OR 1.25, 95% CI 0.847-1.84, P=0.26). There was no association between the Rh blood group
(positive/negative) and the risk for developing postpartum hemorrhage (OR 0.97, 95% CI 0.44-1.4, P=0.422).
Conclusion: Blood type O is not associated with an increased risk for early postpartum hemorrhage or for blood transfusion.
Biography
Mais Ali-Saleh is a Resident Physician in Obstetrics and Gynecology Department, the Lady Davis Carmel Medical Center, Technion University, Rappaport Faculty of
Medicine, Haifa, Israel.
Mais Ali-Saleh, Gynecol Obstet 2018, Volume 8
DOI: 10.4172/2161-0932-C4-033