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Volume 7, Issue 5 (Suppl)
J Palliat Care Med, an open access journal
ISSN: 2165-7386
Geriatrics 2017
September 4-5, 2017
September 4-5, 2017 | Edinburgh, Scotland
Geriatrics Gerontology & Palliative Nursing
7
th
International Conference on
BIO-IMPEDANCE ANALYSIS FOR APPENDICULAR SKELETAL MUSCLE MASS
ASSESSMENT IN (PRE-) FRAIL ELDERLY PEOPLE
Paul JM Hulshof
a
a
Wageningen University, Netherlands
Background & Aims:
Screening populations for skeletal muscle mass (SMM) is important for early detection of sarcopenia.
Our aim was to develop an age specific bio-impedance (BI) prediction equation for the assessment of appendicular skeletal
muscle mass (ASMM) in (pre-) frail elderly people aged 65 and older.
Methods:
Anthropometric, BI and dual-energy X-ray absorptiometry (DEXA) measurements from 106 (pre-) frail elderly
subjects (61 females and 45 males, aged 65-96 years) were used to derive three ASMM prediction equations using multiple
regression analysis: one for single frequency BI measurements at 50 kHz (ASMM50kHz), one for measurements at the
characteristic frequency (ASMMFc) and one for bioelectrical impedance spectroscopy (ASMMBIS). The same data was used
to evaluate an existing prediction equation.
Results:
ASMM50kHz had the best fitting model (r2adj=0.923, SEE=1.19 and a PRESS value=163.4), followed by ASMMFc
(r2adj=0.915, SEE=1.25 and a PRESS value=175.9) andASMMBIS (r2adj =0.915, SEE=1.26 and a PRESS value =177.1). Average
ASMM measured by DEXA and both ASMM50kHz and ASMMFc were comparable. ASMMBIS tended to underestimate
ASMM slightly. An existing prediction equation had a tendency to underestimate ASMM in people with a lower amount of
ASMM and overestimate ASMM in people with a higher amount of ASMM.
Conclusions:
ASMM50kHz was able to measure average ASMM within our population of (pre) frail elderly in a valid way.
However, its predictive power on both individual as population level needs to be confirmed in an independent and larger (pre)
frail elderly population and across multiple institutions and ethnic groups. In addition impedance ratio’s and phase angle as
parameters of muscle mass and cell function integrity require further study.
J Palliat Care Med 2017, 7:5(Suppl)
DOI: 10.4172/2165-7386-C1-012