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Gastro 2016
August 11-12, 2016
Volume 6, Issue 4(Suppl) J Gastrointest Dig Syst 2016
ISSN:2161-069X JGDS, an open access journal
conferenceseries .com
August 11-12, 2016 Birmingham, UK
6th Global Gastroenterologists Meeting
Mona El-Amir, J Gastrointest Dig Syst 2016, 6:4(Suppl)
Living donor liver transplantation (LDLT): A single center experience
Mona El-Amir
Cairo University, Egypt
In the absence of cadaveric donor liver transplantation, Living-Donor Liver Transplantation (LDLT) is an alternative option
for patients with end-stage liver disease. LDLT continues to be a life-saving option in countries without satisfactory cadaveric
donation. In our country, the cadaveric donation is still limited by religious and cultural beliefs, as in Japan, Korea and India.
We reported the outcome of 120 adult LDLTs at Cairo University Transplant Center. Patient’s records were retrospectively
reviewed between 2006 and 2014 for recipient survival and complications. Transplant recipients consisted of 110 men and
10 women (ages 19 to 62 years). The main indication for LDLT was hepatitis C cirrhosis. All procedures were right lobe
hepatectomy without middle hepatic vein. All donors survived the procedure and 64 of 120 LDLT recipients were alive. 30
patients died in the early (first 3 months) post-operative period (25%) because of infections, vascular complications, biliary
complications, CVA and pulmonary embolism. 64% of the donors survived for one year. HCV recurrence occurred in 61
patients (50.8%); biliary complications developed in 47 recipients (39%), where most of them were treated by interventional
technique. Vascular complications occurred in 12 patients (10%). 38 patients suffered from infections (31.6%). Acute rejection
occurred in 21 patients (17.5%); while chronic rejection developed in 7 patients (5.8%). Our results indicate that LDLT is with
rather satisfactory outcome in absence of cadaveric donation.
Biography
Mona El-Amir has completed her MSc from Cairo University, School of Medicine, Egypt. She is a Professor of Internal Medicine, Cairo University. In 2010, she
became a member of European Association for Study of Liver (EASL) as well as of Asian Pacific Association for Study of Liver (APASL). Currently, she is working
as an active member of Liver Transplant Center, Medical School of Cairo University.