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Volume 8 Journal of Gastrointestinal & Digestive System Gastro Meet 2018
August 06-07, 2018
August 06-07, 2018 Abu Dhabi, UAE
Gastroenterology and Digestive
Disorders
16th International Conference on
Direct acting antivirals and hepatocellular carcinoma correlations
M A Ezzel Arab
NHTMRI, Egypt
Hepatocellular Carcinoma (HCC) is increasing worldwide and particularly in Egypt, where the prevalence of hepatitis C
viral (HCV) infection, a well-established HCC risk factor, is the highest in the world. Direct-acting antivirals (DAAs)
have completely changed the panorama of hepatitis C due to their high efficacy and optimal safety profile. The impact of DAA-
based treatment on the incidence of HCC in patients with cirrhosis and particularly on the incidence of HCC recurrence after
successful curative treatment has emerged as a controversial issue with potential clinical implications. As Egypt achieved the
highest number (>1.5 million) of treated patients by DAAs globally up till now, it is so important to evaluate its situation in this
issue. The talk will highlight on the following items: Discrepancy regarding the occurrence and recurrence of HCC, highlight
on some Egyptian studies and possible factors contributing to increased HCC incidence/recurrence by DAAs.
Biography
MAEzzel Arab is a Professor of Internal Medicine and Hepatology. He is the Founder of Intervention and Hepatoma Unit at the National Hepatology and Tropical Medicine
Research Institute (NHTMRI) since 2007. He is a member of the steering committee which put the Egyptian guidelines for HCC (2011) which was sponsored by the
Egyptian Society of Liver Cancer (ESLC).
M A Ezzel Arab, J Gastrointest Dig Syst 2018, Volume 8
DOI: 10.4172/2161-069X-C3-070