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conferenceseries
.com
Volume 7, Issue 4(Suppl)
J Gastrointest Dig Syst, an open access journal
ISSN: 2161-069X
Gastro Congress 2017
September 11-12, 2017
September 11-12, 2017 | Paris, France
12
th
Euro-Global Gastroenterology Conference
Association between colorectal adenoma and hand grip strength
Ji Hyun Moon
1,2
, Ji Eun Lee
3
, Oh Yun Hwan
1,2
, Mi Hee Kong
1,4
and
Hyeon Ju Kim
1,4
1
Jeju National University Hospital, Korea
2
Graduate School of Jeju National University, Korea
3
Seoul National University Hospital, Korea
4
Jeju National University, Korea
O
nly a few studies suggest an association between colorectal adenoma and obesity and their results remain controversial. Previous
studies are primarily focused on obesity caused by increasing fat. However, wasting of muscle also causes obesity. The role of
decreased muscle mass and strength in the development of colorectal polyps is yet unknown. We propose that not only an increase
in fat, but also decreased muscle mass and/or strength can affect the development of colorectal adenomas. We investigated the
association between colorectal adenomas and hand grip strength, which is an easy way to assess muscle condition. Our cross-
sectional study included 957 subjects who underwent colonoscopy at Jeju National University Hospital between 2015 and 2016. Grip
strength was measured twice on the left and right hand alternately, and the grip strength was evaluated as the maximum value of the
arm used. The adenoma group was classified as those showing histologically confirmed colorectal adenoma while the adenoma free
group (control group) included those with an unremarkable abnormal finding on colonoscopy, including colitis and hyperplastic
polyps. Colorectal adenomas were found in 249 men (42.6%) and 85 women (22.8%). In men, hand grip strength was 42.48 kg in the
control group, 41.12 kg in the adenoma group and in women 23.87 kg in the control group and 22.77 kg in the adenoma. Additionally,
there was no significant difference in body fat percentage between the control and adenoma groups when assessed using bioelectrical
resistance measurement in both sexes. After adjusting for age, smoking status, and exercise frequency, log-transformed grip strength
and colorectal adenoma were found to show no significant correlation. The odds ratio (OR) was 1.24 [95% confidence interval (CI)
0.60-2.58, P=0.560] in men and 1.05 (95% CI 0.27-4.03, P=0.946) in women. There was no significant relationship noted between
hand grip strength and colorectal adenoma.
Biography
Ji Hyun Moon works as an Assistant Professor for the Department of Family Medicine at Jeju National University Hospital, Korea.
tropiajh@gmail.comJi Hyun Moon et al., J Gastrointest Dig Syst 2017, 7:4(Suppl)
DOI: 10.4172/2161-069X-C1-053