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conferenceseries
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Volume 7, Issue 4 (Suppl)
J Clin Exp Pathol, an open access journal
ISSN: 2161-0681
Euro Pathology 2017
August 02-03, 2017
13
th
EUROPEAN PATHOLOGY CONGRESS
August 02-03, 2017 Milan, Italy
Human papillomavirus infection in Chinese oropharyngeal squamous cell carcinoma and its
relationship with survival by tissue microarray analysis
Binbin Li
1
and
Huiying He
2
1
Peking University School and Hospital of Stomatology, China
2
Peking University Health Science Center, China
S
quamous cell carcinoma (SCC) in the head and neck region is the sixth most common malignancy throughout the world
today. Given more and more basic and clinical research and reports emerged, its overall 5-year survival rate is still poor.
The further research on its etiology and pathogenesis in different countries and regions may apply new clues for the choice of
therapeutic strategy. It is well known that classical SCC in oral cavity is closely related with the abuse of tobacco and alcohol.
However, 90% of oropharyngeal SCC in North America and Europe is associated with high risk human papillomavirus (HPV)
infections. These HPV+ cases presented more favorable prognosis than HPV- cases. But the infection rate of HPV in Chinese
oropharyngeal SCC was much lower than that in western countries through our study. We also discussed the demographic
characteristics, the relationship between HPV with the differentiation and survival of oropharyngeal SCC.
kqlibinbin@aliyun.comJ Clin Exp Pathol 2017, 7:4(Suppl)
DOI: 10.4172/2161-0681-C1-038