38 / 40
Page 92
Notes:
conferenceseries
.com
Volume 9
Journal of Clinical & Experimental Cardiology
ISSN: 2155-9880
October 22-24, 2018 | Rome, Italy
27
th
European Cardiology Conference
Euro Cardiology 2018
October 22-24, 2018
Ventricular ectopic burden as a predictor for survival in subjects less than 65 years old
Nikhil Sabharwal
1
, Bobby John
2
, Joshua Dunn
2
and
Venkat Vangaveti
1
1
James Cook University, Campus Name, Australia
2
The Townsville Hospital, Australia
P
remature ventricular complexes (PVCs) are widely observed in the general population and are commonly asymptomatic.
Several studies report a poor prognosis in conjunction with underlying structural heart disease (SHD), however, there is
a lack of data implicating their clinical significance in the absence of SHD. A review of literature was conducted to determine
the risk factors predisposing to PVCs. Variables explored in the studies included: age, presence or absence of SHD, PVC
duration/morphology, morbidity and mortality. Data was collected according to the inclusion (age <65, 8 year follow-up, 24-
hour ambulatory monitoring) and exclusion criteria (presence of SHD). Literature review revealed that the presence of PVCs
indicate an increased risk of cardiovascular events (e.g. heart failure) in individuals aged >65 years, and is further amplified by
factors such as PVC duration and morphology. A PVC burden of as low as 10% may significantly increase risk of PVC-induced
cardiomyopathy. The limitations of current literature include: (1) analysis of a 2-minute rhythm strip; (2) short follow-up
periods; and (3) failing to account for underlying SHD in <65 years old. The prognostic value of frequent PVCs in subjects <65
years old without underlying SHD is yet to be explored. A retrospective observational study is being conducted at Townsville
Hospital to further investigate whether presence of PVCs, in health individuals <65 years old, should be treated as a modifiable
risk factor. This will shed light upon whether more aggressive risk factor management is to be implemented and potential of
interventions such as PVC ablation.
Biography
Nikhil Sabharwal is currently a 5
th
year Medical student from James Cook University in Townsville, Australia. He has previously had poster and oral presentations
at the Indian Association of Cardiothoracic Surgery Conference and World Congress of Surgery held in Switzerland in 2017. He is actively involved in teaching and
mentoring of medical students at his university. He is very enthusiastic about research and aspires to pursue a career in academic surgery. His ongoing research
work is entitled: “Women in Cardiac Surgery: An Update” and “Clinical Cardiology and Research: A perspective from Dr Eugene Braunwald”.
Nikhil Sabharwal et al., J Clin Exp Cardiolog 2018, Volume 9
DOI: 10.4172/2155-9880-C10-116