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Volume 7, Issue 5 (Suppl) Epidemiology (Sunnyvale), an open access journal
ISSN: 2161-1165 Epidemiology 2017
October 23-25, 2017
Page 58
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EPIDEMIOLOGY & PUBLIC HEALTH
October 23-25, 2017 | Paris, France
6th International Conference on
Cristina Stasi, Epidemiology (Sunnyvale) 2017, 7:5(Suppl)
DOI: 10.4172/2161-1165-C1-016
GLOBAL BURDEN OF CHRONIC HEPATITIS B VIRUS INFECTION IN PRISON
Statement of the Problem: Despite a vaccine against Hepatitis B Virus (HBV) has been available since 1982, the prevalence
of adult with chronic HBV infection in sub-Saharan Africa and East Asia was estimated to be 5–10%. High rate of chronic
infections is also found in the Amazon and the southern parts of eastern and central Europe. In the Middle East and the Indian
subcontinent, the prevalence is of 2–5%. Less than 1% of the population of Western Europe and North America was chronically
infected. Given the high prevalence of infections such as human immunodeficiency virus (HIV), HBV, and Hepatitis C Virus
(HCV) among inmates, particularly those with a history of injection drug use, prison is considered reservoir facilitating these
infections. The prevalence of HBsAg in prisoners in west and central Africa was very high (23.5%). High levels of chronic HBV
infection were also reported in east and southern Africa (5.7%) and in Eastern Europe and central Asia (10.4%).
Purpose: The purpose of this review is to analyse the most recent data on HBV prevalence and vaccination in prison.
Methodology: Relevant studies were searched on PubMed database. The Centres for Disease Control and Prevention (CDC)
has highlighted the importance of HBV blood screening and the subsequent anti-HBV vaccination in the prison population.
The vaccination was recommended to all inmates and it represents an opportunity to prevent HBV infection in persons at high
risk. In these subjects, an accelerated hepatitis B immunization schedule may result in a rapid seroconversion and practically
in an early short-term protection.
Conclusion & Significance: Although hepatitis B vaccination of inmates has been recommended since the vaccine first became
available in 1982, only some state vaccinate inmates routinely. Therefore, it is necessary to have collaboration between public
health, clinicians and correctional authorities to implement vaccination program.
Biography
Cristina Stasi graduated in Medicine and Surgery at the Catholic University of “Sacro Cuore”, Rome (2001). In 2006 she specialized in Gastroenterology at the University
of Pisa. From 2006 to 2009 she took part in Clinical Research Projects at the University Hospital “Careggi”, Florence. At the same time, she improved her knowledge in
Study Design, Management of Clinical Research Project, Statistics and Epidemiology. In 2013, she received her PhD in Experimental and Clinical Medicine from the Uni-
versity of Florence. She has published about 50 papers in reputed international journals and has been serving as an Editorial Board Member of some international journals.
Cristina Stasi
Regional Health Agency of Tuscany, Italy