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conferenceseries
.com
Volume 7, Issue 2 (Suppl)
J Ecosyst Ecography, an open access journal
ISSN:2157-7625
September 18-20, 2017
September 18-20, 2017 Toronto, Canada
Joint Conference
International Conference on
International Conference on
Environmental Microbiology and Microbial Ecology
&
Ecology and Ecosystems
Drug resistant pattern of bacterial isolates in infected wounds at Bahir Dar Regional Health Research
Laboratory Center, Northwest Ethiopia
Derese Hailu
1
, Awoke Derbie
2
, Daniel Mekonin
2
, wondmagegn Mulu
2
, Yesuf Adem
2
, Alem Tsega
1
and
Fantahun Biadglegne
2
1
Bahir Dar Regional Health Research Laboratory Center, Ethiopia
2
Bahir Dar University, Ethiopia
Background:
An increased antibiotic resistance of bacterial isolates from wound infections is a major therapeutic challenge
for clinicians. The aim of this study was to describe bacterial isolates that caused wound infection and determine their current
antimicrobial susceptibility pattern.
Methods:
We analyzed the records of 380 wound swab samples that have been cultured at Bahir Dar regional health research
laboratory from January, 2013 to December, 2015. Swabs from different wound types were collected aseptically. Antimicrobial
susceptibility test was performed using disc diffusion technique as per the standard protocol. Bacteriological and socio-demographic
data were collected using a standard data collection format. The data was cleared, entered and analyzed for descriptive statistics using
SPSS version 20.
Result:
The overall bacterial isolation rate in this study was at 61.6% (234/380). About 123 (52.6%) of the isolates were gram positive
cocci and 111 (47.4%) were gram negative rods. The predominant isolate was
S. aureus
at 100 (42.7%) followed by
E. coli
33 (14.1%),
P. aeruginosa
26 (11.1%) and
S. pyogenes
23 (9.8%). The overall rate of multidrug resistant (MDR) bacterial pathogens that caused
wound infection was 54.7%. Out of these, 35 (15.1%) of the isolates were resistant to more than five antibiotics. Ampicillin had the
highest resistance rate at 85.9% among gram negative isolates. Whereas the highest resistance rate among gram positive isolates was
in erythromycin at 31.1%.
Conclusion:
In the studied region, higher frequency of mono and multi drug resistance of bacterial pathogens that caused wound
infection was documented. Thus, a new method to the causative agent and antimicrobial susceptibility testing surveillance in areas
where there is no culture facility is needed to assist the health professionals in the selection of appropriate antibiotics.
deresehailu86@gmail.comJ Ecosyst Ecography 2017, 7:2 (Suppl)
DOI: 10.4172/2157-7625-C1-030