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Volume 7, Issue 6 (Suppl)

J Clin Exp Pathol, an open access journal

ISSN:2161-0681

Digital Pathology 2017

November 15-16, 2017

November 15-16, 2017 San Antonio, USA

2

nd

International Conference on

Digital Pathology & Image Analysis

Malignant Triton Tumor of Thigh (MTTT): A case report and review of literature

Anila Chughtai

Chughtai lab, Pakistan

M

alignant triton tumor (MTT) is a tumor arising from Schwann cells with divergent rhabdomyoblastic differentiation.

It is a rare and aggressive variant of malignant peripheral nerve sheath tumor (MPNST). We present a case of 33 years

old male with thigh swelling. Surgical excision was done followed by histopathological and immunohistochemical (IHC)

workup which revealed a tumor showing two types of cell populations including pleomorphic spindle cells and large cells

with pleomorphic eccentric nuclei. Spindle cells showed positivity for S-100 IHC stain confirming their neural origin while

large cells with eccentric nuclei showed positivity for desmin & myogenin IHC stains confirming their rhabdomyoblastic

origin. Hence, the diagnosis of MTT was made. A 5 years survival rate for MTT is 5-15% compared to 50-60% for MPNST.

Considering it is a rare entity with aggressive clinical behavior and poor prognosis, correct diagnosis is essential that can be

achieved by careful histological and IHC evaluation.

Biography

Anila Chughtai has completed her Bachelor of Medicine & Bachelor of Surgery degrees (MBBS) from Services Institute of Medical Sciences, Lahore. Currently, she

is working as a second year Post-graduate trainee at Chughtai lab Lahore.

anee.usman.666@gmail.com

Anila Chughtai, J Clin Exp Pathol 2017, 7:6 (Suppl)

DOI: 10.4172/2161-0681-C1-043