Page 38
Notes:
conferenceseries
.com
Volume 7, Issue 6 (Suppl)
J Clin Exp Pathol, an open access journal
ISSN:2161-0681
Digital Pathology 2017
November 15-16, 2017
November 15-16, 2017 San Antonio, USA
2
nd
International Conference on
Digital Pathology & Image Analysis
Malignant Triton Tumor of Thigh (MTTT): A case report and review of literature
Anila Chughtai
Chughtai lab, Pakistan
M
alignant triton tumor (MTT) is a tumor arising from Schwann cells with divergent rhabdomyoblastic differentiation.
It is a rare and aggressive variant of malignant peripheral nerve sheath tumor (MPNST). We present a case of 33 years
old male with thigh swelling. Surgical excision was done followed by histopathological and immunohistochemical (IHC)
workup which revealed a tumor showing two types of cell populations including pleomorphic spindle cells and large cells
with pleomorphic eccentric nuclei. Spindle cells showed positivity for S-100 IHC stain confirming their neural origin while
large cells with eccentric nuclei showed positivity for desmin & myogenin IHC stains confirming their rhabdomyoblastic
origin. Hence, the diagnosis of MTT was made. A 5 years survival rate for MTT is 5-15% compared to 50-60% for MPNST.
Considering it is a rare entity with aggressive clinical behavior and poor prognosis, correct diagnosis is essential that can be
achieved by careful histological and IHC evaluation.
Biography
Anila Chughtai has completed her Bachelor of Medicine & Bachelor of Surgery degrees (MBBS) from Services Institute of Medical Sciences, Lahore. Currently, she
is working as a second year Post-graduate trainee at Chughtai lab Lahore.
anee.usman.666@gmail.comAnila Chughtai, J Clin Exp Pathol 2017, 7:6 (Suppl)
DOI: 10.4172/2161-0681-C1-043