dermatology-conference-2016_keynote

1 / 6

Volume 7 Issue 8(Suppl) J Clin Exp Dermatol Res
ISSN: 2155-9554 JCEDR, an open access journal
Page 18
Dermatology Conference 2016
November 28-29, 2016
conferenceseries.com
November 28-29, 2016 Melbourne, Australia
10th Asia-Pacific Dermatology Conference
Rodney Sinclair, J Clin Exp Dermatol Res 2016, 7:8(Suppl)
Breakthroughs in the Diagnosis and Treatment of Male and Female Pattern Hair Loss
All men and women experience some degree of hair loss with advancing age. When severe or premature it can cause
significant distress. The diagnosis of androgenetic alopecia can usually be made clinically by visual inspection of the
frontal scalp and examination of follicular units with dermoscopy. In some women further investigations may be required to
identify contributing factors, comorbidities such as polycystic ovary syndrome, diabetes, hypertension and hyperlipidaemia
and exclude other potential differential diagnoses such as chronic telogen effluvium and frontal fibrosingalopecia.Computer
generated 3-D reconstructions of the arrectorpili muscle have delivered a new model for scalp hair growth that explains how
men and women with androgenetic alopecia can lose up to 50% of their scalp hair volume without visible balding; why women
develop diffuse hair loss rather than complete baldness and why hair follicle miniaturization is fully reversible in alopecia areata
but only partially reversible in androgeneticalopecia.Gene associations studies have identified candidate genes and epigenetic
silencing of the androgen receptor gene on the occipital scalp explain the inheritance and pattern of androgeneticalopecia.
Combination therapy of oral antiandrogenand oralminoxidilwith topicalstemoxydine reduce hair shedding, arrest natural
progression and stimulate partial hair regrowth.
Cosmetic camouflage, scalp micropigmentation and hair transplantation complement medical therapy.
Biography
Rodney Sinclair is Professor of Dermatology at the University of Melbourne and Director of SInclair Dermatology. He is Past-President of the Australasian Society
for Dermatology Research, the Australasian Hair and Wool Research Society and the Skin and Cancer Foundation of Victoria.Prof Sinclair is the co-author of the
section on Dermatology in the Oxford Textbook of Medicine, the Hair Chapters in Rook and Bolognaand lead author of Therapeutic Guidelines- Dermatology. He
has written 13 textbooks of dermatology, and has over 400 research publications. Sinclair Dermatology conduct clinical research in psoriasis, hair loss, urticaria,
atopic dermatitis, hidradenitissuppurativa, and skin cancer prevention and treatment as well as laboratory research into stem cell biology, regenerative medicine
and gene discovery.
Rodney Sinclair
University of Melbourne and the Epworth Hospital, Australia