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conferenceseries.com
Volume 7, Issue 3 (Suppl) J Obes Weight Loss Ther, an open access journal
ISSN: 2165-7904 Childhood Obesity & Bariatric Surgery 2017
June 12-13, 2017
June 12-13, 2017 Rome, Italy
& Childhood Obesity and Nutrition
10th International Conference on
Metabolic and Bariatric Surgery
2nd International Conference on
JOINT EVENT
Thyroid function in childhood obesity and metabolic comorbidity
Lucia Pacifico
Sapienza University of Rome, Italy
Childhood obesity is a worldwide health problem and its prevalence is increasing steadily and dramatically all over the world.
Obese subjects have a much greater likelihood than normal-weight children of acquiring dyslipidemia, elevated blood pressure
and impaired glucose metabolism, which significantly increase their risk of cardiovascular and metabolic diseases. Elevated TSH
concentrations in association with normal or slightly elevated free T4 and/or free T3 levels have been consistently found in obese
subjects, but the mechanisms underlying these thyroid hormonal changes are still unclear. Whether higher TSH in childhood
obesity is adaptive, increasing metabolic rate in an attempt to reduce further weight gain or indicates subclinical hypothyroidism or
resistance and thereby contributes to lipid and/or glucose dysmetabolism, remains controversial. My report will highlight current
evidence on thyroid involvement in obese children and discusses the current controversy regarding the relationship between thyroid
hormonal derangements and obesity-related metabolic changes (hypertension, dyslipidemia, hyperglycemia and insulin resistance,
nonalcoholic fatty liver disease) in such population; the possible mechanisms linking thyroid dysfunction and pediatric obesity and;
the potential role of lifestyle intervention as well as of therapy with thyroid hormone in the treatment of thyroid abnormalities in
childhood obesity.
Biography
Lucia Pacifico was a Researcher and Assistant Professor in Pediatrics from 1988. She completed her Medical studies at Sapienza University of Rome from
1971-1977; Residency in Pediatrics at Sapienza University of Rome from 1977-1980 and; Residency in Pediatrics at St. Lukes-Roosevelt Hospital, Columbia
University, USA from 1981-1982. She was Board Certified in Neonatology (Rome, Italy) in 1983. Her research interests include Pediatrics, Infectious Diseases,
Gastroenterology, Hepatology and Nutrition.
Lucia Pacifico, J Obes Weight Loss Ther 2017, 7:3 (Suppl)
DOI: 10.4172/2165-7904-C1-045