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conferenceseries
.com
Volume 7, Issue 3 (Suppl)
J Obes Weight Loss Ther, an open access journal
ISSN: 2165-7904
Childhood Obesity & Bariatric Surgery 2017
June 12-13, 2017
June 12-13, 2017 Rome, Italy
&
Childhood Obesity and Nutrition
10
th
International Conference on
Metabolic and Bariatric Surgery
2
nd
International Conference on
JOINT EVENT
Deficiency in vitamin D and calcium associated comorbidities in overweight children
Ellie Wright
EGW Research Institute LLC, USA
O
besity is increasing in epidemic proportion around the world with most concern for health issues among children. Vitamin D
(25OHD) deficiency is reported in obese children. Low 25OHD levels are associated with dyslipidemia and insulin resistance
with increased risk of cardiovascular complication in adulthood. Studies suggest that a low vitamin D which is linked to dysregulation
of white adipose tissue and that calcium influences adipocyte metabolism. High calcium intake depresses levels of parathyroid
hormone and 1, 25-hydroxy vitamin D. These decreased hormone levels cause decreases in intracellular calcium, thereby inhibiting
lipogenesis and stimulating lipolysis. Dietary Calcium has been also shown to increase faecal fat excretion. Deficiency of vitamin
D in children is linked with further comorbidities in life such as hypertension, myocardial infarction, and stroke, as well as other
cardiovascular-related diseases, such as diabetes associated with impairment of cooperative signaling from the 1,25-(OH)(2)D(3)-
activated vitamin D receptor (VDR). Vitamin D and calcium insufficiency causes cellular dysfunction in many organs and could
increase the risk of diseases, particularly of osteoporosis, colorectal and breast cancer, inflammatory bowel disease, insulin-dependent
diabetes mellitus type I, metabolic syndrome, diabetes mellitus type II, hypertensive and cardiovascular disease. This research focuses
on the mechanisms by which calcium and vitamin D could regulate body weight and adiposity and prevent future health issues in
children.
Biography
Ellie Wright completed her Bachelor of Arts and master degree at arizona state university. she completed her graduate certificate in geriatric and gerontology at
university of arizona. in 2015, she completed her doctoral degree in naturopathic medicine at southwest college of naturopathic medicine, USA. she is a passionate
researcher in natural medicine, prevention and cure.
elliewright@cox.netEllie Wright, J Obes Weight Loss Ther 2017, 7:3 (Suppl)
DOI: 10.4172/2165-7904-C1-045