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conferenceseries
.com
Volume 8
Journal of Obesity & Weight Loss Therapy
ISSN: 2165-7904
Childhood Obesity 2018
March 15-16, 2018
March 15-16, 2018 | Barcelona, Spain
11
th
International Conference on
Childhood Obesity and Nutrition
An investigation of causal relationshipbetween age at introduction of formula feeding or solids and incidence
of childhood overweightness or obesity in Greater Western Sydney Australia: A prospective cohort study
Haider Mannan
1
and
Praween Senanayake
2
1
Translational Health Research Institute-Western Sydney University, Australia
2
Western Sydney University, Australia
Background:
Epidemiological evidence suggests that timing of introduction of formula-feeding or solid foods may be
associated with subsequent overweight or obesity, and the association may vary by any breastfeeding at first year for four
months or more versus not.
Methods:
We included 346 infants from South Western Sydney using the Longitudinal Study of Australian Children (LSAC)
who at baseline examination were singleton births, neither overweight nor obese (weight for age<97.7
th
percentile), and were
full term births (gestational age>39 weeks). The primary outcome was time to the occurrence of first overweight or obesity at
ages 2, 4, 6, 8 and 10 of the child. Risk of overweight or obesity was defined as body mass index (BMI)≥85
th
percentile, using
the National Centre for Health Statistics curves. The primary exposure variable of interest was age at introduction to formula
or solid foods (<4, and ≥4 months). Missing data were estimated using multivariate normal imputation (MVNI) based on 25
imputations. We used Cox proportional hazards regression to assess the temporal association between age at introduction to
formula or solids and the timing of occurrence of incident overweight or obesity at ages 2, 4, 6, 8 and 10 of the child and test
whether the association between age at introduction to formula or solids and timing of occurrence of incident overweight or
obesity was modified by any breastfeeding at first year (≥4 months versus not); with and without adjusting for mother’s BMI,
age, education during pregnancy, race and social disadvantage (SEIFA).
Results:
The risk of overweight or obesity was significantly higher among infants introduced to formula or solids at <4 months
compared to those introduced at ≥4 months in both unadjusted and adjusted analyses. We found strong interaction between
age at formula or solids introduction and breastfeeding for four or more months and subsequent risk of incident overweight or
obesity. The risk of overweight or obesity by age at formula or solids introduction decreased with increase in any breastfeeding
duration to four or more months.
Conclusions:
Timing of introduction to formula or solids within four months was a risk factor of incident childhood overweight
or obesity for children 10 years later; so increasing the prevalence of exclusive breast-feeding to more than four months would
be a worthwhile public health measure. Increasing any breastfeeding duration to at least four months would help to further
decrease the risk of childhood overweight or obesity.
Biography
Haider Mannan is a Biostatistician and Epidemiologist having subject knowledge of comorbid obesity and eating disorders among Australian adults as well as
obesity as a risk factor of diabetes, cardiovascular diseases and disability. He has been developing research track record in the broad area of obesity research with
his recent interest and focus been on eating disorders among obese adults in the South Australian population. He has published his papers in some top ranked
obesity and epidemiology journals which include
International Journal of Obesity, American Journal of Epidemiology, Obesity and Annals of Epidemiology.
h.mannan@westernsydney.edu.auHaider Mannan et al., J Obes Weight Loss Ther 2018, Volume 8
DOI: 10.4172/2165-7904-C1-057