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Page 58

conferenceseries

.com

6

th

World Congress on

October 16-18, 2017 | San Francisco, USA

Breast Cancer & Therapy

Volume 2, Issue 5 (Suppl)

Breast Can Curr Res, an open access journal

Breast Cancer Congress 2017

October 16-18, 2017

Plantago Ovata

(Esfarzeh) in prevention and treatment of acute radiation dermatitis

Ali Tavakoli

Shiraz University of Medical Sciences, Iran

Introduction:

Plantago Ovata

is one of medicinal plants for treatment of dermatitis with a long history of use in traditional medicine

(TM) references. New studies have also proved its antioxidant, immunomodulatory, anti-inflammatory and wound healing properties.

The aim of this study is to suggest a compound derived from

Plantago Ovata

(taken from TM) for treatment of acute radiation

dermatitis (ARD).

Results:

In TM, the seed isolated from

Plantago ovata

called “Esfarzah” is considered as an anti-inflammatory drug, so topical

application of it is recommended for treatment of dermatitis. It is also moisturizing, softener and skin fattening in its properties, that

increases skin flexibility. This latter property (moisturizing) is an ideal method for preventing and minimizing skin reactions that is

generally agreed in a systematic review. Esfarzah would be useful to treat dermatitis if mixed with rose oil and soaked in water until

its mucilage is extracted and then applied topically. This traditional formulation with this method of preparation is our suggestion for

treatment of ARD. However, it is required that this formulation be prepared in form of cream and on industrial scale.

Conclusions:

We claim that this compound not only is moisturizing, which increases skin flexibility and helps in keeping trans

epidermal water (a measure for skin barrier integrity) that is effective for prevention of ARD, but also relieves inflammation as well

as skin healing due to creating mucilage that is effective for treatment of ARD. So, it is imperative that researches be performed to

prove these therapeutic effects.

tavakkolia@sums.ac.ir

Breast Can Curr Res 2017, 2:5 (Suppl)

DOI: 10.4172/2572-4118-C1-012